Rchr
J-GLOBAL ID：200901090408829973
Update date: Apr. 24, 2025
Murata Michio
ムラタ ミチオ | Murata Michio
Affiliation and department：
Job title：
specially appointed professor
Homepage URL (1)：
http://www.chem.sci.osaka-u.ac.jp/lab/murata/
Research field (3)：
Bioorganic chemistry
, Biochemistry
, Molecular biochemistry
Research keywords (7)：
Biophysics of lipid bilayer membranes
, Solid state NMR
, Bioorganic Chemistry
, Natural Product Chemistry
, NMR
, Bioorganic Chemsitry
, Natural product chemistry
Research theme for competitive and other funds (32)：
- 2023 - 2026 Average orientation of lipid acyl chains in the domain structure of model membranes
- 2021 - 2025 Chemical study on dynamics of model lipid bilayers reproducing biomembrane under non-equilibrium conditions
- 2017 - 2022 Dynamic conformation and domain structure of lipid molecules in model biomembranes
- 2017 - 2022 Frontiers in Chemical Communications
- 2016 - 2021 Dynamic conformation and domain structure of lipid molecules in model biomembranes
- 2019 - 2021 Roles of lipid anchors and minor components in domain formation in biomembranes
- 2016 - 2018 Depth-dependent melting of acyl chains and phase-transition of lipid bilayers
- 2013 - 2017 Exploration of natural products and small molecues for mode-of-action study on biomembrane lipids
- 2014 - 2016 Lipid-water interactions involved in membrane biofunctions
- 2013 - 2016 Elucidation of Mechanisms on Membrane Protein Integration by a Glycolipid Acting Like an Enzyme
- 2013 - 2015 Structral analysis of amphotericin B channel complex using solid-state NMR
- 2012 - 2015 Study on biosynthesis and secretion mechanisms of the sperm attracting factor in ascidians
- 2012 - 2014 Rapid conformational change results in attractive interactions between biomolecules
- 2009 - 2011 分子プローブを用いた脂質ラフトにおけるタンパク質-リン脂質相互作用の構造基盤解明
- 2009 - 2010 生体小分子の化学構造と生理機能を結ぶ弱い分子間相互作用の記述
- 2008 - 2010 Analysis of molecular assemblage in lipid bilayers using bicelles
- 2006 - 2010 Structures and Functions of Membrane-Bound Biomolecules
- 2003 - 2005 Structure of Molecular Assembles of Bioactive Natural Products Formed in Biomembranes
- 1999 - 2003 Targeted Pursuit of Challenging Bioactive Molecules
- 2000 - 2002 Frontier in Structure Elucidation of Natural Products
- 1998 - 2000 Molecular Mechanism of Action for Particularly Potent Marine Biotoxins.
- 1998 - 2000 Practical Configuration Analysis for Natural Products.
- 1998 - 1999 弱い相互作用と生理活性:ポリアミン-核酸複合体の構造
- 1997 - 1997 新分子の発見と21世紀の天然物化学
- 1996 - 1997 Membrane Protein Recognition by Ladder-shaped Polyether Compounds
- 1996 - 1996 大型ポリエーテル系超活性天然物の機能解明
- 1995 - 1995 超活性大型天然物の機能解明
- 1994 - 1995 Complete Structure Elucidation of Maitotoxin
- 1994 - 1994 マイトトキシンなどの大型海洋天然物の機能解明
- 1992 - 1992 蛋白脱りん酸化酵素阻害剤・オカダ酸の機能解明のための化学修飾
- 1992 - 1992 3次元NMRを用いた天然物の構造決定法の開発
- 1987 - 1987 さんご礁海域における魚類の毒化調査
Show all
Papers (328)：
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Tomokazu Yasuda, Daiki Ueura, Madoka Nakagomi, Shinya Hanashima, Michio Murata. Relevance of ceramide 1-phosphate domain formation in activation of cytosolic phospholipase A2. Biophysical Chemistry. 2025. 107433-107433
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Shinya Hanashima, Ayana Yamanaka, Yuki Ibata, Tomokazu Yasuda, Yuichi Umegawa, Michio Murata. Lipid Compositions of Liquid-Ordered and Liquid-Disordered Phases in Ternary Membranes of Sphingomyelin, Cholesterol, and Dioleoylphosphatidylcholine Determined by 2H NMR: Stearoyl-Sphingomyelin Compared with Its Palmitoyl Counterpart. Langmuir. 2024
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Darcy Garza-Miyazato, Shinya Hanashima, Yuichi Umegawa, Michio Murata, Masanao Kinoshita, Nobuaki Matsumori, Peter Greimel. Mode of molecular interaction of triterpenoid saponin ginsenoside Rh2 with membrane lipids in liquid-disordered phases. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2024. 1866. 7. 184366-184366
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Tomokazu Yasuda, Daiki Ueura, Madoka Nakagomi, Shinya Hanashima, J Peter Slotte, Michio Murata. Design, synthesis of ceramide 1-phosphate analogs and their affinity for cytosolic phospholipase A2 as evidenced by surface plasmon resonance. Bioorganic & medicinal chemistry letters. 2024. 129792-129792
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Yuichi Umegawa, Sho Kato, Sangjae Seo, Wataru Shinoda, Satoshi Kawatake, Shigeru Matsuoka, Michio Murata. Protein-lipid acyl chain interactions: Depth-dependent changes of segmental mobility of phospholipid in contact with bacteriorhodopsin. Biophysical chemistry. 2024. 308. 107204-107204
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MISC (153)：
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南裕介, 真鍋良幸, 真鍋良幸, 小野莉紗子, 平尾宏太郎, 梅川雄一, 村田道雄, 深瀬浩一, 深瀬浩一. Conformational and dynamics analysis of dolichol and dolichol phosphate using solid-state NMR. 日本化学会春季年会講演予稿集(Web). 2024. 104th
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宮内龍, 秋田穂, 日下裕規, 田所高志, 杉山成, 相羽俊彦, 相羽俊彦, 深瀬浩一, 村田道雄, 井貫晋輔, et al. CD1d-アミド型抗原複合体のX線結晶構造解析と示差走査熱量計による熱安定性解析. 日本結晶学会年会講演要旨集. 2024. 2024
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南裕介, 真鍋良幸, 真鍋良幸, 小野莉紗子, 平尾宏太郎, 梅川雄一, 村田道雄, 深瀬浩一, 深瀬浩一. Synthesis of 13C, 2H-labeled dolichol phosphate for conformational analysis of dolichol using Solid State NMR. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
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南裕介, 真鍋良幸, 真鍋良幸, 小野莉紗子, 平尾宏太郎, 梅川雄一, 村田道雄, 深瀬浩一, 深瀬浩一. Conformational and dynamics analysis of dolichol and dolichol phosphate by solid state NMR. 日本糖質学会年会要旨集. 2023. 42nd
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喜多俊介, 秋田穂, 日下裕規, TIAN Cong, 田所高志, 井貫晋輔, 新山真由美, 杉山成, 村田道雄, 藤本ゆかり, et al. X-ray crystal structure analysis of MHC class I like molecule CD1d in complex with glycolipids. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
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Patents (1)：
Works (15)：
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脂質活性構造プロジェクト
2010 -
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Bioactive Lipid Structures
2010 -
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分子複合体としての生体膜の構造と機能
2009 -
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分子複合体としての生体膜の構造と機能
2008 -
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分子複合体としての生体膜の構造と機能
2007 -
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Professional career (1)：
Work history (5)：
- 2024/04 - 現在 Osaka University Institute for Protein Research Specially Apointed Professor
- 1999/04 - 2024/03 Graduate School of Science, Osaka University Department of Chemistry Professor
- 2011 - 2017 Japan Science and Technology Agency ERATO Lipid Active Structure Project Reserach Director
- 1993 - 1999 Graduate School of Science, The University of Tokyo Chemsitry Department Associate Professor,
- 1985 - 1993 Faculty of Agriclture, Tohoku University Reseach Associate
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