Nishimaki-Mogami Tomoko

モガミトモコ | Nishimaki-Mogami Tomoko

Affiliation and department：

Research keywords (6)：核内受容体 , リポ蛋白 , 脂質代謝 , Nuclear receptor , Lipoprotein , Lipid Metabolism

Research theme for competitive and other funds (5)：

2017 - 2023 結晶性インフラマソーム活性化異物の認識機構とスタチンによる制御の解明
2014 - 2018 RXR agonists and tributyltin have the ability to induce white-to-brown fat conversion.
2011 - 2013 Control of multiwall carbon nanotube-induced inflammatory responses by cellular cholesterol
2008 - 2010 Molecular basis for cell-type specific HDL generation by selective LXR modulators
1998 - 2000 The role of N-linked glycosylation on the assembly and secretion of VLDL

Papers (95)：

Tomoko Nishimaki-Mogami, Shosuke Ito, Hongyan Cui, Takumi Akiyama, Norimasa Tamehiro, Reiko Adachi, Kazumasa Wakamatsu, Yoshiaki Ikarashi, Kazunari Kondo. A cell-based evaluation of human tyrosinase-mediated metabolic activation of leukoderma-inducing phenolic compounds. Journal of dermatological science. 2022. 108. 2. 77-86
Hitomi Tanaka, Shosuke Ito, Makoto Ojika, Tomoko Nishimaki-Mogami, Kazunari Kondo, Kazumasa Wakamatsu. The Oxidation of Equol by Tyrosinase Produces a Unique Di-ortho-Quinone: Possible Implications for Melanocyte Toxicity. International journal of molecular sciences. 2021. 22. 17
Hongyan Cui, Keisuke Soga, Norimasa Tamehiro, Reiko Adachi, Akiko Hachisuka, Akihiko Hirose, Kazunari Kondo, Tomoko Nishimaki-Mogami. Statins repress needle-like carbon nanotube- or cholesterol crystal-stimulated IL-1β production by inhibiting the uptake of crystals by macrophages. Biochemical pharmacology. 2021. 188. 114580-114580
Naoki Teno, Yukiko Yamashita, Arisa Masuda, Yusuke Iguchi, Keisuke Oda, Ko Fujimori, Takie Hiramoto, Tomoko Nishimaki-Mogami, Mizuho Une, Keigo Gohda. Identification of potent farnesoid X receptor (FXR) antagonist showing favorable PK profile and distribution toward target tissues: Comprehensive understanding of structure-activity relationship of FXR antagonists. Bioorganic & medicinal chemistry. 2019. 27. 11. 2220-2227
Kosuke Nakamura, Takumi Ishigaki, Tomoko Kobayashi, Shinya Kimata, Keisuke Soga, Uki Fujii, Masahiro Kishine, Reona Takabatake, Junichi Mano, Kazumi Kitta, et al. Identification of chickpea (Cicer arietinum) in foods using a novel real-time polymerase chain reaction detection method. Journal of Food Composition and Analysis. 2018. 71. 8-16

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MISC (8)：

簾内桃子, 河村麻衣子, 曽我慶介, 蜂須賀暁子, 最上知子, 宇佐見誠, 関野祐子, 袴塚高志, 花尻瑠理[木倉]. 新規流通危険ドラッグ4-acetoxy-N,N-diethyltryptamineの代謝に関する研究. 日本薬学会年会要旨集. 2017. 137年会. 3. 234-234
酒井信夫, 安達玲子, 中村亮介, 木村美恵, 山本幸子, 菊地博之, 渡邉敬浩, 佐々木和実, 西嶋桂子, 安宅花子, et al. 化粧品による健康被害抗原性を呈する加水分解コムギの分子プロファイリング. アレルギー. 2014. 63. 3-4. 508-508
唐澤未来, 中村亮介, 酒井信夫, 安達玲子, 斎藤嘉朗, 最上知子, 山崎壮, 手島玲子. EXiLE法を用いた牛乳アレルギー患者IgEに応答する乳糖中に含まれるアレルゲンの解析. 日本食品衛生学会学術講演会講演要旨集. 2013. 106回. 83-83
Akihiko Hirose, Mutsuko Hirata-Koizumi, Sakiko Fujii, Masatoshi Furukawa, Hina Kato, Atsushi Ono, Tomoko Nishimaki-Mogami, Tetsuji Nishimura. Carbon chain length dependent toxic potency by longer-chain perfluorocarbonic acids. TOXICOLOGY LETTERS. 2012. 211. S184-S185
Tomoko Nishimaki-Mogami, Hongyan Cui, Keiichiro Okuhira, Mikihiko Naito, Kazuhiro Suzuki, Nishimura Tetsuji, Akihiko Hirose. Mechanism underlying multiwall carbon nanotube-induced IL-1beta secretion. TOXICOLOGY LETTERS. 2012. 211. S201-S201

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Education (3)：

1981 - 1984 東北大学薬学研究科博士課程
1979 - 1981 Tohoku University
- 1979 Tohoku University Faculty of Pharmaceutical Sciences Department of Pharmacy

Professional career (1)：

Ph. D. (Tohoku University)

Work history (8)：

2021/04 - 現在国立医薬品食品衛生研究所生化学部客員研究員
2016/04 - 2021/03 国立医薬品食品衛生研究所主任研究官(再任用)
2014 - 2016/03 国立医薬品食品衛生研究所生化学部部長
2013 - 国立医薬品食品衛生研究所代謝生化学部部長
2007 - 国立医薬品食品衛生研究所機能生化学部室長

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Association Membership(s) (6)：

日本薬学会 , 日本生化学会 , 日本脂質生化学研究会 , The Pharmaceutical Society of Japan , The Japanese Biochemical Society , Japanese Conference on the Biochemistry of Lipids

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