Rchr

J-GLOBAL ID：200901093849576824 Update date: May. 10, 2020

Ambo Akihiro

アンボアキヒロ | Ambo Akihiro

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (2)：ペプチド合成 , peptide synthesis

Research theme for competitive and other funds (2)：

オピオイドペプチドの合成と構造活性相関
Synthesis and conformation-activity relationship of opioid peptide analogs

MISC (14)：

A Ambo, H Niizuma, A Sasaki, H Kohara, Y Sasaki. Dermorphin tetrapeptide analogues with 2',6'-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high mu opioid receptor binding and biological activities. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2003. 13. 7. 1269-1272
Endomorphin 2 analogues containing Dmp residue as an aromatic amino acid surrogate with high mu-opioid receptor affinity and selectivity. Bioorganic & Medicinal Chemistry. 2003. 11, 675-678
A Ambo, T Terashima, Y Sasaki. Novel [D-Arg(2)]dermorphin(1-4) analogs with mu-opioid receptor antagonist activity. CHEMICAL & PHARMACEUTICAL BULLETIN. 2002. 50. 10. 1401-1403
A Ambo, H Murase, H Niizuma, H Ouchi, Y Yamamoto, Y Sasaki. Dermorphin and deltorphin heptapeptide analogues: Replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2002. 12. 6. 879-881
A Ambo, H Murase, H Niizuma, H Ouchi, Y Yamamoto, Y Sasaki. Dermorphin and deltorphin heptapeptide analogues: Replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2002. 12. 6. 879-881

ｍore...

Education (4)：

- 1989 東北薬科大学薬学研究科衛生化学
- 1989 Tohoku Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences
- 1987 東北薬科大学薬学部薬学科
- 1987 Tohoku Pharmaceutical University Faculty of Pharmaceutical Science

Professional career (2)：

(BLANK) (Tohoku Pharmaceutical University)
(BLANK) (Tohoku Pharmaceutical University)

Association Membership(s) (2)：

日本ペプチド学会 , 日本薬学会

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