Wako Hiroshi

ワコヒロシ | Wako Hiroshi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.f.waseda.jp/wako/

Research field (1)： Biophysics

Research keywords (1)： Protein folding, Bioinformatics

Research theme for competitive and other funds (15)：

2016 - 2019 Development of intra-molecule dynamic structure network analysis method to characterize protein dynamics
2006 - 2008 Normal mode analysis of proteins using an elastic network model in dihedral angle space
2005 - 2007 Analyses of binding normal modes in protein complexes and registration to the database ProMode
2003 - 2005 A comparative study of dynamic structures of proteins by using normal mode analysis database.
1999 - 2001 Classification and analysis of local structure motifs in protein conformations

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Papers (62)：

Hiroshi Wako, Shigeru Endo. Dynamic properties of oligomers that characterize low-frequency normal modes. Biophysics and Physicobiology. 2019. 16. 0. 220-231
Shigeru Endo, Hiroshi Wako. Normal mode analysis calculation for a full-atom model with a smaller number of degrees of freedom for huge protein molecules. Biophysics and Physicobiology. 2019. 16. 0. 205-212
Yuko Tsuchiya, Yoshiki Namiuchi, Hiroshi Wako, Hiromichi Tsurui. A study of CDR3 loop dynamics reveals distinct mechanisms of peptide recognition by T-cell receptors exhibiting different levels of cross-reactivity. Immunology. 2018. 153. 4. 466-478
Hiroshi Wako, Shigeru Endo. Normal mode analysis as a method to derive protein dynamics information from the Protein Data Bank. Biophysical Reviews. 2017. 9. 6. 877-893
Akira R. Kinjo, Gert-Jan Bekker, Hiroshi Wako, Shigeru Endo, Yuko Tsuchiya, Hiromu Sato, Hafumi Nishi, Kengo Kinoshita, Hirofumi Suzuki, Takeshi Kawabata, et al. New tools and functions in data-out activities at Protein Data Bank Japan (PDBj). Protein Science. 2017. 27. 1. 95-102

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Books (16)：

Study of Folding/Unfolding Kinetics of Lattice Proteins by Applying a Simple Statistical Mechanical Model for Protein Folding
Nova Biomedical 2011 ISBN:9781617619229
科学技術は社会とどう共生するか(分担執筆): 「科学技術ジャーナリストの課題」(パネルディスカッションの記録)
東京電機大学出版局 2009 ISBN:9784501624309
トポロジーデザイニング新しい幾何学からはじめる物質・材料設計(分担執筆): 「タンパク質のモチーフ構造解析」
(株)エヌ・ティー・エヌ 2009
バイオインフォマティクス事典 (分担執筆): 「構造エネルギー最適化法」「基準振動解析」の項目
共立出版 2006
複雑系の構造と予測 (分担執筆): 「タンパク質分子の立体構造転移」
共立出版 2006

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Lectures and oral presentations (107)：

タンパク質の基準振動モードのネットワーク解析:中心性指標Betweennessと活性部位
(第17回日本蛋白質科学会年会 2017)
タンパク質の基準振動モードのネットワーク解析:中心性指標の計算
(第54回日本生物物理学会年会 2016)
T細胞受容体による特異的および交差反応的な抗原認識機構の解明
(第54回日本生物物理学会年会 2016)
二面角系基準振動解析プログラムの巨大分子への適用-側鎖自由度の固定
(第16回日本蛋白質科学会年会 2016)
動的構造解析に基づく特異性および交差性を有するTCRの抗原認識機構の解明
(第16回日本蛋白質科学会年会 2016)

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Education (2)：

- 1978 Waseda University Graduate School, Division of Science and Engineering Physics and Applied Physics
- 1973 Waseda Universsity Faculty of Science and Engineering Department of Physics

Professional career (1)：

Dr. of Science (Waseda University)

Work history (6)：

1993 - 現在 Waseda University, Professor
1988 - 1993 Waseda University, Assistant Professor
1986 - 1988 Waseda University, Lecturer
1985 - 1986 Juntendo University, Research Assistant
1982 - 1985 Waseda University, Research Assistant

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Association Membership(s) (5)：

The Chem-Bio Informatics Society , Japanese Society for Bioinformatics , Protein Science Society of Japan , The Physical Society of Japan , The Biophysical Society of Japan

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