Rchr
J-GLOBAL ID：200901094812303689   Update date: Apr. 17, 2024

Fujiwara Toshimichi

フジワラ トシミチ | Fujiwara Toshimichi
Affiliation and department：
Osaka University Institute for Protein Research

About Osaka University Institute for Protein Research


Job title： Professor
Research field  (2)： Biophysics ,  Basic physical chemistry
Research keywords  (7)： Solid-state NMR ,  NMR ,  Protein ,  Biophysics ,  蛋白質 ,  核磁気共鳴 ,  生物物理学
Research theme for competitive and other funds  (33)：
  • 2021 - 2024 Multi-scale structural analysis of membrane protein in cells by hyperpolarized NMR
  • 2014 - 2018 In situ Protein NMR Structure Analysis
  • 2014 - 2018 Site selective cellular analysis by solid-state NMR
  • 2014 - 2016 Protein NMR method developed for macromolecular complex
  • 2012 - 2014 New NMR methods developed for structure determination of large proteins
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Papers (226)：
  • Kazuya Nagano, Tomohiro Nakao, Mariko Takeda, Haruna Hirai, Hikaru Maekita, Michiko Nakamura, Naoki Imakawa, Ayako Egawa, Toshimichi Fujiwara, Jian Qing Gao, et al. Polyglycerol fatty acid ester contributes to the improvement and maintenance of water solubility of amorphous curcumin by suppressing the intermolecular interaction and the diffusion rate of curcumin. Food Chemistry. 2024. 437. Pt 2. 137866-137866
  • Koya Sakuma, Naohiro Kobayashi, Toshihiko Sugiki, Toshio Nagashima, Toshimichi Fujiwara, Kano Suzuki, Naoya Kobayashi, Takeshi Murata, Takahiro Kosugi, Rie Tatsumi-Koga, et al. Design of complicated all-α protein structures. Nature Structural and Molecular Biology. 2024. 31. 2. 275-282
  • Shintaro Minami, Naohiro Kobayashi, Toshihiko Sugiki, Toshio Nagashima, Toshimichi Fujiwara, Rie Tatsumi-Koga, George Chikenji, Nobuyasu Koga. Exploration of novel αβ-protein folds through de novo design. Nature Structural and Molecular Biology. 2023. 30. 8. 1132-1140
  • K. Miyanishi, T. Sugiki, T. Matsui, R. Ozawa, Y. Hatanaka, H. Enozawa, Y. Nakamura, T. Murata, A. Kagawa, Y. Morita, et al. Protein-Ligand Interaction Analyses with Nuclear Magnetic Resonance Spectroscopy Enhanced by Dissolution Triplet Dynamic Nuclear Polarization. The Journal of Physical Chemistry Letters. 2023. 14. 27. 6241-6247
  • Toshihiko Sugiki, Akihiro Ito, Yuko Hatanaka, Masaki Tsukamoto, Tsuyoshi Murata, Koichiro Miyanishi, Akinori Kagawa, Toshimichi Fujiwara, Masahiro Kitagawa, Yasushi Morita, et al. Real-time monitoring of enzyme-catalyzed phosphoribosylation of anti-influenza prodrug favipiravir by time-lapse nuclear magnetic resonance spectroscopy. NMR in Biomedicine. 2023. 36. 5. e4888
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MISC (433)：
  • 藤井汐美, 児玉高志, 杉木俊彦, 花田賢太郎, 藤原敏道, 児嶋長次郎, 児嶋長次郎. Aggregation of the CERT START domain and its prevention. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
  • 榎本麻由, 安澤すあい, 小泉優香, 古板恭子, 田岡健一郎, 田岡健一郎, 西田敬二, 近藤昭彦, 児玉高志, 藤原敏道, et al. イネ花成ホルモン蛋白質複合体によるLLPS形成と花成制御機構. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
  • 板坂佑真, 小篭蒼, 古板恭子, 杉木俊彦, 若松馨, 内田紀之, 石田康博, 相田卓三, 藤原敏道, 児嶋長次郎, et al. Development of RDC measurement method for protein using titanium oxide nanosheets and non-detergent sulfobetaines. Abstracts. Annual Meeting of the NMR Society of Japan. 2022. 61st
  • 櫻林修平, 櫻林修平, 古板恭子, 山田剛史, 藤原敏道, 中谷和彦, 児嶋長次郎, 児嶋長次郎. DNA recognition mechanism of naphthyridine dimer, a CGG repeat-binding drug, analyzed by NMR. Abstracts. Annual Meeting of the NMR Society of Japan. 2022. 61st
  • 古板恭子, 児玉高志, 児玉高志, 児玉高志, 杉木俊彦, 赤木謙一, 物部容子, 榎園能章, 門田典子, 中村光咲, et al. In-cell NMR study using human cells: Analysis of protein three-dimensional structure and dynamics. Abstracts. Annual Meeting of the NMR Society of Japan. 2022. 61st
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Patents (14)：
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Books (16)：
  • 13C-13C Distance Measurements by Polarization Transfer Matrix Analysis of 13C Spin Diffusion in Uniformly 13C-labeled Molecular Complex under Magic-angle Spinning
    Royal Society of Chemistry 2014
  • 13C-13C Distance Measurements by Polarization Transfer Matrix Analysis of 13C Spin Diffusion in Uniformly 13C-labeled Molecular Complex under Magic-angle Spinning
    Royal Society of Chemistry 2014
  • Isotope labeling and NMR spectroscopy of proteins
    Kagaku Doujin 2009
  • Isotope labeling and NMR spectroscopy of proteins
    Kagaku Doujin 2009
  • タンパク質の同位体ラベルとNMR分光法
    化学同人 2009
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Works (24)：
  • 固体NMR膜蛋白質複合体構造解析技術
    2009 -
  • 蛋白質解析用超高感度テラヘルツ波NMR装置
    2009 -
  • H+-ATP合成酵素膜内在Foの機能構造と不正規構造の固体NMRによる解明
    2009 -
  • 生体系NMRデータベースBMRBの構築と高度化、蛋白質構造データバンクの国際的な構築と高度化
    2009 -
  • 固体NMRによる7回膜貫通蛋白質複合体の構造解析
    2009 -
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Education (2)：
  • 1980 - 1985 Osaka University Graduate School of Science Department of Chemistry
  • 1976 - 1980 Osaka University School of Science Department of Chemistry
Professional career (2)：
  • Doctor of Science (Osaka University)
  • Doctor of Science
Work history (7)：
  • 2023/04 - 現在 Osaka University Professor Emeritus
  • 2008/04 - 2023/03 Osaka University Institute for Protein Research professor
  • 2007 - 2008 Osaka University Institute for Protein Research
  • 2000 - 2007 Osaka University Institute for Protein Research Associate Professor
  • 1996/01 - 2000/12 横浜国立大学 工学部 物質工学科 助教授
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Committee career (5)：
  • 2021/12 - 現在 International Society of Magnetic Resonance Fellow
  • 2022/04 - 2024/03 Nuclear Magnetic Resonance Society of Japan President
  • 2008/04 - 2024/03 Nuclear Magnetic Resonance Society of Japan Administration officer
  • 2018/04 - 2020/03 Osaka University Aide to University President
  • 2013/04 - 2014/03 Osaka University Chairperson of committee for human rights issues
Awards (1)：
  • 2019/11 - The Society of Electron Spin Science and Technology Development of high sensitivity magic-sample spinning NMR by dynamic nuclear polarization
Association Membership(s) (9)：
The Society of Electron Spin Science and Technology ,  International Society of Magnetic Resonance ,  The Chemical Society of Japan ,  電子スピンサイエンス学会 ,  International Society of Magnetic Resonance ,  日本核磁気共鳴学会 ,  日本蛋白質科学会 ,  日本化学会 ,  日本生物物理学会
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