Rchr
J-GLOBAL ID:200901094952584750   Update date: Jan. 31, 2024

Shinohara Akira

シノハラ アキラ | Shinohara Akira
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.protein.osaka-u.ac.jp/genome/index.html
Research field  (2): Molecular biology ,  Genetics
Research keywords  (1): 分子生物学
Research theme for competitive and other funds  (34):
  • 2019 - 2022 Molecular mechanisms of control of recombination by dynamics of RAD51/DMC1-DNA complexes
  • 2015 - 2020 Chromosome OS
  • 2015 - 2020 Control of chromosome functions by axis-loop structure (chromosome 3D) during meiosis
  • 2016 - 2019 Molecular mechanism of partner choice for recombination by two RecA homologs
  • 2014 - 2016 Functions of nuclear actin filament and its mechanism of the formation
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Papers (93):
  • Suman Dash, Sameer Joshi, Ajith V Pankajam, Akira Shinohara, Koodali T Nishan. Heterozygosity alters Msh5 binding to meiotic chromosomes in the baker’s yeast. Genetics. 2023
  • Masaru Ito, Yurika Fujita, Akira Shinohara. Positive and negative regulators of RAD51/DMC1 in homologous recombination and DNA replication. DNA Repair. 2023. 103613-103613
  • Ghanim Fajish V, Kiran Challa, Sagar Salim, Ajith VP, Stephen Mwaniki, Ruihao Zhang, Yurika Fujita, Masaru Ito, Nishant K.T, Akira Shinohara. DNA double-strand breaks regulate the cleavage-independent release of Rec8-cohesin during yeast meiosis. Genes-to-Cells. 2023. in press
  • Sijia Liu, Akira Shinohara, Asako Furukohri. Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA binding and ATPase activities. Journal of Biological Chemistry. 2023. 105424-105424
  • Masaru Ito, Asako Furukohri, Kenichiro Matsuzaki, Yurika Fujita, Atsushi Toyoda, Akira Shinohara. FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination. Nature Communications. 2023. 14. 1. 6857
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MISC (52):
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Lectures and oral presentations  (20):
  • Fignl1 AAA+ ATPase modulates the dynamics of Rad51 and Dmc1 ensembles
    (Chromosome stability 2022 2022)
  • 減数分裂期のDNA交換と 染色体構造形成の制御のメカニズム
    (神戸大学理学部生物科学科セミナー 2022)
  • Fignl1 AAA+ ATPase modulates the dynamics of Rad51 and Dmc1 ensembles
    (FASEB meeting on recombination and genome rearrangement 2022)
  • Control of homologous recombination during meiosis and mitosis
    (ANSC Reproductive Physiology, University of Illinois at Urbana-Champaign Urbana, USA 2022)
  • Human RAD51 paralog, SWSAP1, promotes RAD51 assembly by regulating the anti-recombinase, FIGNL1 AAA+ ATPase
    (Seminar at IISER Thiruvananthapuram 2019)
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Works (12):
  • 減数分裂期染色体機能部位におけるプロテインプロファイリング
    2004 -
  • 減数分裂期組換えと生殖細胞形成
    2004 -
  • 相同組換えによるゲノム安定化を介した発ガンの防御
    2004 -
  • 真核生物の相同組換えの分子メカニズムの解明
    2004 -
  • 酵母Rad52蛋白質の生化学的解析
    1990 - 1993
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Education (5):
  • 1988 - 1991 Osaka Univ. Graduate School of Science
  • - 1991 Osaka University Graduate School, Division of Natural Science
  • 1986 - 1988 Osaka University Graduate School of Science
  • 1982 - 1986 Osaka Univ. School of Science Department of Biology
  • - 1986 Osaka University Faculty of Science
Professional career (2):
  • Ph.D. (Osaka University)
  • (BLANK)
Work history (9):
  • 2001 - 2003 大阪大学院理学研究科 助教授
  • 2003 - - 大阪大学たんぱく質研究所 教授
  • 2001 - - Osaka Univ. Graduate School of Science, Assistant Prof.
  • 1999 - 2000 シカゴ大学 準教授
  • 1999 - 2000 University of Chicago, Assistant Professor
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Awards (3):
  • 2021/04 - Awards for Science and Technology Study on molecular mechanism of homologous recombination
  • 2009 - 大阪市 大阪府 大阪科学技術センター 大阪科学賞
  • 1992 - 日本分子生物学会 東燃研究奨励賞
Association Membership(s) (1):
日本分子生物学会
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