J-GLOBAL ID:200901094952584750   Update date: Jul. 31, 2020

Shinohara Akira

シノハラ アキラ | Shinohara Akira
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.protein.osaka-u.ac.jp/genome/index.html
Research field  (2): Molecular biology ,  Genetics
Research theme for competitive and other funds  (3):
  • Molecular analysis of meiotic recombination
  • Biochemical characterization of yeast Rad51、Rad52 proteins
  • Studies on function of recombination gene, RAD51, in human and mouse
Papers (79):
  • Tai-Ting Woo, Chi-Ning Chuang, Mika Higashide, Akira Shinohara, Ting-Fang Wang. Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks. Nucleic Acids Research. 2020
  • Zhu, Z, Bani, I, Shinohara, M, A. Shinohara. SCF(Cdc4) ubiquitin ligase regulates synaptonemal complex formation during meiosis. BioRxiv. 2020
  • G.N. Krishnaprasada, V.P. Ajith, Shinohara, M, Chakraborty, P, Lin, G. Steinmetz, L.M, Shinohara, A, Nishant K.T. The baker’s yeast Msh4-Msh5 binds to double-strand break hotspots distant to chromosome axis to promote crossovers. BioRxiv. 2020
  • Lee, M.-S, Higashide, M, Hong, S, Lee, K, Shinohara, A, Shinohara, M, K.P. Kim. Synaptonemal complex central regions modulates crossover pathways and feedback control of meiotic double-strand break formation. BioRxiv. 2020
  • Rei Nouchi, Hiroaki Aihara, Fumie Arie, Makoto Asashima, Hiroyuki Daida, Jun, Fudano, Yasuhiro Fujiwara, Shinji Fushiki, Robert J, Geller, Kazuo Hatano, Toshio Homma, Minoru Kimura, Toshio Kuroki, Koichi, Miki, Ikuo Morita, Kosaku Nitta, Akira Shinohara, Mikiko C, Siomi, Masayuki Yoshida, Iekuni Ichikawa. Toward Global Standardization of Conducting Fair Investigations of Allegations of Research Misconducts. Accountability in Research: Policies and Quality Assurance. 2020. 27. 6. 327-346
MISC (40):
  • Challa Kiran, Miki Shinohara, Akira Shinohara. Prophase pathway of arm-cohesin removal in budding yeast meiosis. GENES & GENETIC SYSTEMS. 2014. 89. 6. 278-278
  • Terasawa, Masahiro, Shinohara, Akira, Shinohara, Miki. Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability. CANCER SCIENCE. 2014. 105. 12. 1519-1525
  • Masaaki Miyamoto, Yuta Tsukamoto, Chisako Katayama, Miki Shinohara, Akira Shinohara, Shohei Maekawa. The small GTPase Rab5 controls cell morphology, sexual development, ion-stress response and vacuolar formation in fission yeast. FASEB JOURNAL. 2014. 28. 1
  • Santosh Kumar Gothwal, Takehiko Usui, Miki Shinohara, Akira Shinohara. Roles of Pal1 complex in Meiosis of Budding Yeast. GENES & GENETIC SYSTEMS. 2013. 88. 6. 379-379
  • Challa Kiran, Hbd Prasad Rao, Miki Shinohara, Akira Shinohara. Regulatory mechanism of nuclear envelope remodelling during budding yeast meiosis. GENES & GENETIC SYSTEMS. 2013. 88. 6. 379-379
Lectures and oral presentations  (16):
  • Human RAD51 paralog, SWSAP1, promotes RAD51 assembly by regulating the anti-recombinase, FIGNL1 AAA+ ATPase
    (Seminar at IISER Thiruvananthapuram 2019)
  • Human RAD51 paralog, SWSAP1, promotes RAD51 assembly by regulating the anti-recombinase, FIGNL1 AAA+ ATPase
    (Emerging Concepts in Chromosome Biology”,at IMP Vienna 2019)
  • Human RAD51 paralog, SWSAP1, promotes RAD51 assembly by regulating the anti-recombinase, FIGNL1 AAA+ ATPase
    (Seminar at UC Davis, USA 2019)
  • Human RAD51 paralog, SWSAP1, promotes RAD51 assembly by regulating the anti-recombinase, FIGNL1 AAA+ ATPase
    (Keystone symposium on DNA Replication and Genome Instability: From Mechanism to Disease 2019)
  • Control of Rad51-assembly and disassembly by Rad51 paralogues and anti-recombinases
    (Chromosome stability meeting, Bangalore, India 2018)
Works (4):
  • Biochemical characterization of Rad52 protein
    1990 - 1993
  • Analysis of functions of RAD51 and DMC1 in meiosis
    1993 -
  • Biochemical characterization of Rad51 protein from yeast.
    1993 -
  • Characterization of functional domains of E. coli RecA protein by intragenic suppressors
    1985 - 1989
Education (5):
  • 1988 - 1991 Osaka Univ. Graduate School of Science
  • - 1991 Osaka University Graduate School, Division of Natural Science
  • 1986 - 1988 Osaka University Graduate School of Science
  • 1982 - 1986 Osaka Univ. School of Science Department of Biology
  • - 1986 Osaka University Faculty of Science
Professional career (2):
  • Ph.D. (Osaka University)
  • (BLANK)
Work history (4):
  • 2001 - - Osaka Univ. Graduate School of Science, Assistant Prof.
  • 1999 - 2000 University of Chicago, Assistant Professor
  • 1991 - 1993 Post-doctral fellow
  • 1993 - - Osaka Univ. Faculty of Science, Research Associate
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