Research field (5)：
Pharmaceuticals - health and biochemistry
, Molecular biology
, Genetics
, Environmental effects of chemicals
, Environmental effects of radiation
Research keywords (9)：
genotoxicity
, gene mutation
, Environmental mutagens
, mutant frequency
, Spi- assay
, gpt assay
, transgenic mouse
, environmental mutagen
, in vivo mutagenesis
Research theme for competitive and other funds (11)：
2020 - 2024 遺伝情報発現と遺伝子突然変異の相関
2019 - 2023 A study on DNA damages in germ cells of male mice and germline mutations induced in the offspring
2017 - 2020 Analysis of mutagenesis relating to DNA topology, transcription and DNA repair
2013 - 2016 Studies on quantitative evaluation of inherited germline mutations
2013 - 2015 Assessment of current lung cancer and related health risk by past-exposure of particulates suspended in air
2010 - 2013 Studies on mechanisms underlying genotoxic thresholds through genetic modification of DNA polymerase zeta
2006 - 2009 Studies on roles of translesion DNA synthesis in thresholds for genotoxic substances
2006 - 2006 1分子PCR法を用いた次世代遺伝毒性試験法の開発
2004 - 2005 Study on the Mechanisms Underlying Endogenous Hepatocarcinogenesis Induced Only by the Manipulation of Food Composition
化学物質や放射線などによってマウス個体に誘発される 点突然変異と欠失変異の解析
in vivo mutagenicity test of environmental mutagens using transgenic rodent mutation assay
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Papers (101)：
Ken Kuroda, Yuji Ishii, Shinji Takasu, Aki Kijima, Kohei Matsushita, Ken-Ichi Masumura, Takehiko Nohmi, Takashi Umemura. Possible contribution of 8-hydroxydeoxyguanosine to gene mutations in the kidney DNA of gpt delta rats following potassium bromate treatment. Mutation research. Genetic toxicology and environmental mutagenesis. 2024. 894. 503729-503729
Soichiro Hagio, Naho Tsuji, Satoshi Furukawa, Kazuya Takeuchi, Seigo Hayashi, Yusuke Kuroda, Masamitsu Honma, Kenichi Masumura. Effect of sampling time on somatic and germ cell mutations induced by acrylamide in gpt delta mice. Genes and Environment. 2021. 43. 1
Yasunobu Aoki, Mizuki Ohno, Michiyo Matsumoto, Michi Matsumoto, Kenichi Masumura, Takehiko Nohmi, Teruhisa Tsuzuki. Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice. Genes and environment : the official journal of the Japanese Environmental Mutagen Society. 2021. 43. 1. 27-27
Kenichi Masumura, Tomoko Ando, Akiko Ukai, Sho Fujiwara, Shigeo Yokose, Xinyue You, Takayoshi Suzuki, Hiroyuki Hayashi, Takehiko Nohmi, Hisayoshi Takagi, et al. New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay. Genes and environment : the official journal of the Japanese Environmental Mutagen Society. 2021. 43. 1. 25-25
Yuji Ishii, Shinji Takasu, Petr Grúz, Kenichi Masumura, Kumiko Ogawa, Takehiko Nohmi, Takashi Umemura. The role of DNA polymerase ζ in benzo[a]pyrene-induced mutagenesis in the mouse lung. Mutagenesis. 2021. 36. 2. 155-164
2022/04 - 現在 National Institute of Health Sciences Division of Risk Assessment Division Head
2012/10 - 2022/03 National Institute of Health Sciences Division of Genetics and Mutagenesis Section Chief
2004/04 - - 国立医薬品衛生研究所変異遺伝部主任研究官
1996/04 - - 国立医薬品衛生研究所変異遺伝部研究員
1996 - - Researcher, National Institute of Health Sciences
Awards (1)：
2008 - 日本環境変異原学会研究奨励賞
Association Membership(s) (8)：
Environmental Mutagenesis and Genomics Society
, 日本癌学会
, 日本分子生物学会
, 日本環境変異原学会
, Environmental Mutagen Society
, The Japanese Cancer Association
, The Molecular Biology Society of Japan
, The Japanese Environmental Mutagen Society
