Rchr
J-GLOBAL ID：200901096655575745
Update date: Jan. 30, 2024
Okamoto Akihiro
オカモト アキヒロ | Okamoto Akihiro
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Affiliation and department：
Tokai University Student Achievement Center
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Detailed information
Job title：
Associate Professor
Research field (1)：
Structural biochemistry
Research keywords (5)：
酵素学
, 蛋白質工学
, X線結晶構造解析
, reaction mechanism
, enzyme
Research theme for competitive and other funds (6)：
2000 - 2001 トレオニン アルドラーゼによる光学異性体分子の識別機構
1995 - 1996 高品質結晶によるアミノ基転移酵素の反応中間体の高分解能構造解析
1994 - 1994 オリゴマー蛋白質の耐熱化機構
1993 - 1993 高品質結晶によるアミノ基転移酵素の反応中間体の高分解能構造解析
酵素反応機構の解析
Analysis of Enzymatic Reaction mechanism
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Papers (28)：
Seiji Ishii, Takato Yano, Akihiro Okamoto, Takeshi Murakawa, Hideyuki Hayashi. Boundary of the nucleotide-binding domain of Streptococcus ComA based on functional and structural analysis. Biochemistry. 2013. 52. 15. 2545-55
Seiji Ishii, Takato Yano, Akio Ebihara, Akihiro Okamoto, Miho Manzoku, Hideyuki Hayashi. Crystal Structure of the Peptidase Domain of Streptococcus ComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway. JOURNAL OF BIOLOGICAL CHEMISTRY. 2010. 285. 14. 10777-10785
Hiroko Ikushiro, Mohammad Mainul Islam, Akihiro Okamoto, Jun Hoseki, Takeshi Murakawa, Shigeru Fujii, Ikuko Miyahara, Hideyuki Hayashi. Structural Insights into the Enzymatic Mechanism of Serine Palmitoyltransferase from Sphingobacterium multivorum. JOURNAL OF BIOCHEMISTRY. 2009. 146. 4. 549-562
Hiroko Ikushiro, Akihiro Okamoto, Hideyuki Hayashi. Structural biology of sphingolipid synthesis. Sphingolipid Biology. 2006. 483-492
Akio Ebihara, Akihiro Okamoto, Yukihide Kousumi, Hitoshi Yamamoto, Ryoji Masui, Norikazu Ueyama, Shigeyuki Yokoyama, Seiki Kuramitsu. Structure-based functional identification of a novel heme-binding protein from Thermus thermophilus HB8. Journal of Structural and Functional Genomics. 2005. 6. 1. 21-32
ｍore...
MISC (5)：
岡本明弘, 中井由実, 林秀行, 広津建, 鏡山博行. Multiple Substrate Recognition Mechanism in Aromatic Amino Acid Aminotransferase. 日本化学会講演予稿集. 1998. 74th. 2. 1333
岡本明弘, 大植慎也, 中井由実, 石井誠志, 林秀行. 基質認識に於いて活性部位のflexibilityが果たす役割 芳香族アミノ酸アミノ基転移酵素の多重基質認識機構の解析. タンパク質構造討論会講演要旨集. 1998
大植慎也, 岡本明弘, 中井由実, 中平雅清, 柴谷武爾, 林秀行, 鏡山博行. Model enzyme of Paracoccus denitrificans aromatic amino acid aminotransferase - aromatic ring and carboxyl group recognition mechanism research. 日本分子生物学会年会プログラム・講演要旨集. 1996. 19th. 129
Crystal structure of aspartate aminotransferase from Thermus thermophilus. Nihon Kessho Gakkaishi. 1996. 38. Supplement. 112-112
S KURAMITSU, S KAWAGUCHI, A OKAMOTO. ENZYMES THAT RECOGNIZE 2 DIFFERENT KINDS OF SUBSTRATE. PROTEIN ENGINEERING. 1994. 7. 9. 1152-1153
Books (3)：
植物バイオテクノロジー
幸書房 2009
新生化学実験講座 第1巻 VII. タンパク質
東京化学同人 1993
蛋白質 核酸 酵素 37
共立出版 1992
Education (4)：
- 1992 Osaka City University
- 1992 Osaka City University Graduate School, Division of Natural Science
1982 - 1988 Faculty of Science, Osaka City University Deparment of Chemistry
- 1988 Osaka City University Faculty of Science
Professional career (2)：
Ph.D. in Chemistry (Osaka City University)
博士(理学) (大阪市立大学)
Work history (6)：
2013/04 - 現在 Tokai University Student Achievement Center
2004/04 - 2013/03 Tokai University
1994/10 - 2004/03 Osaka Medical College
1994/10 - 2004/03 Osaka Medical College Research Assistant
1992/04 - 1994/09 Osaka University School of Science
1992/04 - 1994/09 Osaka University Research Assistant
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Association Membership(s) (3)：
PROTEIN SCIENCE SOCIETY OF JAPAN
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN
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