Research field (1):
Pharmaceuticals - chemistry and drug development
Research keywords (2):
医薬品化学
, Medicinal chemistry
Research theme for competitive and other funds (8):
2022 - 2025 Study of pain relief of sinomenine and related compounds for chemotherapy-induced peripheral neuropathy
2005 - 2005 脳内在性アミンを利用した神経細胞保護物質の合成と保護作用の評価
2001 - 2002 Synthesis and neuroprotection of endogenous brain amine, tetrahydroisoquinoline derivatives for experimental parkinson 's animals
1999 - 2000 Study on the Synthesis of Nitrogen Heterocycles Relsted to the Drugs of Parkison's Disease
テトラヒドロイソキノリン類のドーパミン神経細胞保護作用に関する研究
Pummerer型閉環反応を利用したパーキンソン病関連複素環化合物の合成研究
Studies of Neuroprotection effect of tetrahydroisoquinolines on dopaminergic neron
Syuthesis of the Heterocycles via Pummerer-Type Reaction
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Papers (20):
Toshiaki Saitoh, Michikazu Kitabatake, Yuuko Sugihara, Yuuki Ono, Yoshie Horiguchi, Kunihiko Mohri. SHORT SYNTHESIS OF 5-SUBSTITUTED-2,3,4,5-TETRAHYDRO-BENZO[f][1,4]THIAZEPINES BY USING A MODIFIED PICTET-SPENGLER REACTION. HETEROCYCLES. 2017. 94. 6. 1063-1073
Toshiaki Saitoh, Michikazu Kitabatake, Takuya Sugimoto, Hiromu Kawakubo, Kunihiko Mohri, Yoshie Horiguchi. FACILE AND SHORT-STEP SYNTHESIS OF 5-SUBSTITUTED 2,3,4,5-TETRAHYDROBENZO[f][1,4]OXAZEPINES USING A MODIFIED PICTET-SPENGLER REACTION. HETEROCYCLES. 2017. 94. 2. 342-349
Michikazu Kitabatake, Aki Hashimoto, Toshiaki Saitoh, Takehiro Sano, Kunihiko Mohri, Yoshie Horiguchi. AN EFFICIENT AND CONVENIENT SYNTHESIS OF 4,5,6,7-TETRAHYDROTHIENO[3,2-c]PYRIDINES BY A MODIFIED PICTET-SPENGLER REACTION VIA A FORMYLIMINIUM ION INTERMEDIATE. HETEROCYCLES. 2010. 81. 8. 1903-1921
Michikazu Kitabatake, Toshiaki Saitoh, Takehiro Sano, Yoshie Horiguchi. FACILE SYNTHESIS OF 1-ARYL-2,3-DIHYDRO-1H-ISOINDOLES BY CYCLIZATION OF N-FORMYLIMINIUM ION VIA GEOMETRICALLY DISFAVORED 5-ENDO-TRIG PROCESS. HETEROCYCLES. 2009. 78. 5. 1177-1181
Toshiaki Saitoh, Aki Yamashita, Kenji Abe, Keita Ogawa, Michikazu Kitabatake, Kyoji Taguchi, Yoshie Horiguchi. Synthesis of chiral 3-methyl- and 3-methyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline and prevention of MPP+-induced cytotoxicity. Medicinal Chemistry. 2008. 4. 6. 531-538