Research keywords (6)：
Bacterial photosynthesis
, Protein engineering
, glycoconjugate
, lectin
, androgen
, prostate
Research theme for competitive and other funds (28)：
2015 - 2018 Small leucine-rich repeat proteoglycans associated with mature insoluble elastin serve as binding sites for galectins
2011 - 2014 Carbohydrate recognition mechanisms of galectins and carbohydrate processing enzymes deduced from X-ray structures
2008 - 2010 Modulation of interferon action by intrinsic galectin-9 in cultured human endothelial cells.
2005 - 2006 ガレクチンによる糖鎖認識を介した白血球活性化の分子機構
2005 - 2006 Molecular mechanism of leukocyte activation by galectin via integrin family
2004 - 2005 Regulation of matrix metalloproteinase activity via sugar chain
2003 - 2004 ガレクチンファミリーによる初期発生制御と生体防御システム成立機構
2003 - 2004 Analysis of the role of galectin family and its signaling in the host-response to infection and inflammation.
2003 - 2003 ガレクチンファミリーを介した自然免疫系の活性化と感染応答の分子基盤
2002 - 2002 ガレクチンファミリーを介した自然免疫系の活性化と感染応答の分子基盤
2001 - 2002 Functional Analysis of Galectin-9 and Purification of Galectin-9 Binding Molecules on Cell Surface
2001 - 2001 ガレクチンファミリーを介した自然免疫系の活性化と感染応答の分子基盤
2000 - 2001 Drug design based on the three-dimensional structure of collagen-binding domain, and its application
2000 - 2001 Prostaspanin: A novel member of tetraspanin superfamily specifically expressed in the prostate
1998 - 1999 Role of mutant E-cadherin and epithelin in invasion and metastasis of bladder tumor cells
1998 - ガレクチンの構造と機能
1998 - Structure and function of galectins
1996 - 1997 Isolation and characterization of rat urinary bladder cancer cell lines with different invasive activities
1995 - 1996 Novel urinary and tissue factors which stimulategrowth and motility of bladder tumor cells.
1994 - 1995 Changes in gene activity of growth factors and their receptorsand the contentsof growth factors in urine during bladder carcinogenesis.
1995 - コラーゲン結合ドメインを利用した機能性融合蛋白質の作製と応用
1995 - Production and utilization of functional fusion proteins having collagen-binding domain
1992 - 1993 The role of extracellular matrix in growth and differentiation of prostatic cells
1990 - 1991 Growth/differentiation modulator produced by prostate stromal cells
1988 - 1989 The role of growth factors in the prostate.
1986 - 1987 The role of growth factors and stroma on proliferation and differetiation of the prostate epithelial cells.
1981 - 前立腺における男性ホルモン作用
1981 - Androgenic action in the prostate
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Papers (139)：
Yasuhiro Nonaka, Takashi Ogawa, Hiroki Shoji, Nozomu Nishi, Shigehiro Kamitori, Takanori Nakamura. Crystal structure and conformational stability of a galectin-1 tandem-repeat mutant with a short linker. Glycobiology. 2021
Yasuhiro Nonaka, Takashi Ogawa, Hiroki Shoji, Nozomu Nishi, Shigehiro Kamitori, Takanori Nakamura. Modulation of the carbohydrate-binding specificity of two Xenopus proto-type galectins by site-directed mutagenesis. Biochimica et biophysica acta. Proteins and proteomics. 2021. 1869. 10. 140684-140684
The role of IgE glycosylation in regulation of mast cell degranulation: Identification and structural analysis of galectin-9-binding glycans
(第85回日本生化学会大会 2012)
Optimization of inter-domain structure of galectin-9 for recombinant production
(第85回日本生化学会大会 2012)
