Kyakumoto Seiko

• 2008 - 歯根膜由来細胞からの血管様構造の形成とそのシグナルの解析
• 2005 - 口腔癌細胞の浸潤、転移の分子機構
• 2005 - Oral cancer invasion and progression
• 1998 - 分子シャペロンとシグナル伝達
• 1998 - Molecular chaperone and signal transduction
1988 - ヒト顎下腺腺癌細胞の増殖と分化の制御機構
1988 - Mechanism of transcription activation of target genes by retinoic acid receptors.
1988 - Mechanism of the regulation of proliferation, differentiation, and apoptosis of human salivary gland adenocarcinoma cell line.

• Ohta M, Chosa N, Kyakumoto S, Yokota S, Okubo N, Nemoto A, Kamo M, Joh S, Satoh K, Ishisaki A. IL-1β and TNF-α suppress TGF-β-promoted NGF expression in periodontal ligament-derived fibroblasts through inactivation of TGF-β-induced Smad2/3- and p38 MAPK-mediated signals. International journal of molecular medicine. 2018. 42. 3. 1484-1494
• Miho Ibi, Sawa Horie, Seiko Kyakumoto, Naoyuki Chosa, Mariko Yoshida, Masaharu Kamo, Masato Ohtsuka, Akira Ishisaki. Cell-cell interactions between monocytes/macrophages and synoviocyte-like cells promote inflammatory cell infiltration mediated by augmentation of MCP-1 production in temporomandibular joint. Bioscience Reports. 2018. 38. 2
• Akira Nemoto, Naoyuki Chosa, Seiko Kyakumoto, Seiji Yokota, Masaharu Kamo, Mamoru Noda, Akira Ishisaki. Water-soluble factors eluated from Surface pre-reacted glass-ionomer filler promote osteoblastic differentiation of human mesenchymal stem cells. Molecular Medicine Reports. 2018. 17. 3. 3448-3454
• Naoki Takizawa, Naoto Okubo, Masaharu Kamo, Naoyuki Chosa, Toshinari Mikami, Keita Suzuki, Seiji Yokota, Miho Ibi, Masato Ohtsuka, Masayuki Taira, et al. Bone marrow-derived mesenchymal stem cells propagate immunosuppressive/anti-inflammatory macrophages in cell-to-cell contact-independent and-dependent manners under hypoxic culture. EXPERIMENTAL CELL RESEARCH. 2017. 358. 2. 411-420
• Seiji Yokota, Naoyuki Chosa, Seiko Kyakumoto, Hitomichi Kimura, Miho Ibi, Masaharu Kamo, Kazuro Satoh, Akira Ishisaki. ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2017. 39. 4. 799-808

ｍore...

• Kamada, H, Kamo, M, Kyakumoto, S. Galectin-1 in human oral squamous cell calcinoma cells mediates suppression of anoikis. Dent. J. Iwate Med. Univ. 2007. 32. 157-169
• 加茂雅晴, 客本斉子, 佐藤詔子. ヒト顎下腺由来腺癌細胞株のプロテオミクス. 日本口腔組織培養学会誌. 2006. 15. 11-28
• Minami, J, Kamo, M, Kyakumoto, S. Gene expression in human salivary gland cells on three-dimensional culture comprised in collagen sponge. Dent. J. Iwate Med. Univ. 2005. 30. 216-227
• Taira, M, Chosa, N, Sasaki, K. Effect of the medium type, serum amount and dexamethasone induction on the cell proliferation and alkaline phosphatase activity of twice-passaged SD rat's bone marrow stroma cells. J. Oral Tissue Engin. 2004. 1. 1. 59-68
• Kito Noriko, Kyakumoto Seiko, Chosa Naoyuki. Involvement of HSP90 in anti-Fas-induced apoptosis signaling in the human salivary gland adenocarcinoma cell line HSG. J. Oral Biosci. 2004. 46 (3)229-242. 3. 229-242

ｍore...

• - 1978 Yamagata University Faculty of Science
• - 1978 Yamagata University Faculty of Science

• Doctor of Dentistry (Iwate Medical University)

• 1996 - 日本口腔組織培養研究会学術奨励賞
• 1995 - 歯科基礎医学会賞
• 1995 - Award for Japanese Association for Oral Biology

The Endocrine Society (USA) ,  日本口腔組織培養学会 ,  日本唾液腺学会 ,  歯科基礎医学会 ,  日本癌学会 ,  日本内分泌学会 ,  日本生化学会 ,  The Japanese Association for Oral Biology ,  The Japan Endocrine Society ,  The Japanese Cancer Association ,  The Japanese Biochemistry Society ,  The Endocrine Society (USA)