Art

J-GLOBAL ID：201702227560486746   Reference number：17A1481099

Bone marrow-derived mesenchymal stem cells propagate immunosuppressive/anti-inflammatory macrophages in cell-to-cell contact-independent and -dependent manners under hypoxic culture

骨髄由来間葉系幹細胞は低酸素培養下での細胞-細胞接触非依存性及び依存性様式でimmunosuppressive/anti炎症性マクロファージを増殖させる【Powered by NICT】

Author (17)： Takizawa Naoki (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Takizawa Naoki (Division of Periodontology, Department of Conservative Dentistry, School of Dentistry, Iwate Medical University, 1-3-27 Chuo-dori, Morioka-shi, Iwate 020-8505, Japan) ,  Okubo Naoto (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Okubo Naoto (Laboratory of Pathophysiology and Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Hokkaido 060-0812, Japan) ,  Kamo Masaharu (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Chosa Naoyuki (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Mikami Toshinari (Department of Oral Pathology, School of Dentistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Suzuki Keita (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Suzuki Keita (Division of Periodontology, Department of Conservative Dentistry, School of Dentistry, Iwate Medical University, 1-3-27 Chuo-dori, Morioka-shi, Iwate 020-8505, Japan) ,  Yokota Seiji (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Ibi Miho (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Ibi Miho (Department of Molecular and Cellular Pharmacology, Iwate Medical University School of Pharmaceutical Sciences, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Ohtsuka Masato (Department of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan) ,  Taira Masayuki (Department of Biomedical Engineering, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Yaegashi Takashi (Division of Periodontology, Department of Conservative Dentistry, School of Dentistry, Iwate Medical University, 1-3-27 Chuo-dori, Morioka-shi, Iwate 020-8505, Japan) ,  Ishisaki Akira (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan) ,  Kyakumoto Seiko (Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University, 2-1-1 Nishitokuta, Yahaba-cho, Shiwa-gun, Iwate 028-3694, Japan)
Material： Experimental Cell Research  (Exp Cell Res)
Volume： 358  Issue： 2  Page： 411-420  Publication year： 2017 
JST Material Number： B0313A  ISSN： 0014-4827  CODEN： ECREAL  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Immunosuppressive/anti-inflamm...

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Thesaurus term： coculture ,  receptor ,  *Bone Marrow ,  differentiation (biology) ,  interleukin ,  *mesenchymal cell ,  *Inflammation ,  monocyte ,  secretion (physiology) ,  *oxygen deficiency ,  Cell Adhesion ,  ICAM ,  *macrophage ,  cell culture ,  M2 macrophage ,  cell junction ,  binding and coupling

Author keywords (6)： Mesenchymal stem cells ,  Monocytes/macrophages ,  M2 macrophage ,  Co-culture ,  Bone marrow cell culture ,  Cell adhesion

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (11)： 骨髄由来間葉系幹細胞 ,  低酸素 ,  培養 ,  細胞 ,  細胞接触 ,  非依存性 ,  依存性 ,  様式 ,  炎症 ,  マクロファージ ,  増殖