Art

J-GLOBAL ID：200902070845664757   Reference number：90A0230964

2-Hydroxy-1-substituted-1,2,3,4-tetrahydro-β-carbolines. The Pictet-Spengler reaction of N-hydroxytryptamine with aldehydes.

2-ヒドロキシ-1-置換-1,2,3,4-テトラヒドロ-β-カルボリン N-ヒドロキシトリプタミンとアルデヒドとのPictet-Spengler反応

Author (4)： HINO T (Chiba Univ., Chiba, JPN) ,  HASEGAWA A (Chiba Univ., Chiba, JPN) ,  LIU J-J (Chiba Univ., Chiba, JPN) ,  NAKAGAWA M (Chiba Univ., Chiba, JPN)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 38  Issue： 1  Page： 59-64  Publication year： Jan. 1990 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： olefin compound ,...
Semi thesaurus term： Pictet-Spengler反応 ,...

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JST classification (2)： Other condensed derivatives of pyridine  (CF07097Y) ,  Cyclization reaction,ring-opening reaction  (CF02050I)

Substance index (14)： N-Hydroxytryptamine ,  N-Benzylidene-1H-indole-3-(ethanamine)N-oxide ,  N-(3-Methylbutylidene)-1H-indole-3-(ethanamine)N-oxide ,  N-[2-(1H-Indol-3-yl)ethyl]hexan-1-imine-N-oxide ,  N-[2-(1H-Indol-3-yl)ethyl]-3-methyl-2-buten-1-imine N-oxide ,  N-[2-(1H-Indol-3-yl)ethyl]-3-phenyl-2-propen-1-imine N-oxide ,  N-[2-(1H-Indol-3-yl)ethyl]-α-(2-pyrrolyl)methanimine N-oxide ,  1-Phenyl-1,2,3,4-tetrahydro-β-carboline-2-ol ,  2-Hydroxy-1-(2-methylpropyl)-1,2,3,4-tetrahydro-β-carboline ,  2-Hydroxy-1-pentyl-1,2,3,4-tetrahydro-β-carboline ,  2-Hydroxy-1-(2-methyl-2-propenyl)-1,2,3,4-tetrahydro-β-carboline ,  2-Hydroxy-1-(2-phenylvinyl)-1,2,3,4-tetrahydro-β-carboline ,  2-Hydroxy-1-(2-pyrrolyl)-1,2,3,4-tetrahydro-β-carboline ,  1-(2-Methylpropyl)-3,4-dihydro-β-carboline

Reference (24)：

• 1) K.L. Rinehart, Jr., J. Kobayashi, G.C. Harbour, R.G. Hughes, Jr., S.A. Mizsak, and T.A. Scahill, J. Am. Chem. Soc., 106, 1524 (1984
• K.L. Rinehart, Jr., J. Kobayashi, G.C. Harbour, J. Gilmore, M. Mascal, T.G. Holt, L.S. Shield, and F. Lafargne, J. Am. Chem. Soc., 109, 3378 (1987)
• J.W. Blunt, R.J. Lake, and M.H.G. Munro, Tetrahedron Lett., 28, 1825 (1987)
• R.J. Lake, M.M. Brennan, J.W. Blunt, and M.H.G. Munro, Tetrahedron Lett., 29, 2255 (1988).
• 2) S.Y. Han, M.V. Lakshmikantham, and M.P. Cava, Heterocycles, 23, 1671 (1985).

Terms in the title (3)： 置換 ,  β-カルボリン ,  アルデヒド