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J-GLOBAL ID:200902103367204074   Reference number:01A0544951

Oral Administration of Dimethylarsinic Acid, a Main Metabolite of Inorganic Arsenic, in Mice Promotes Skin Tumorigenesis Initiated by Dimethylbenz(a)anthracene with or without Ultraviolet B as a Promoter.

無機ひ素の主代謝物としてジメチルアルシン酸のマウスへの経口投与はプロモーターとしてのUVBの有無の条件下ジメチルベンゾ(a)アントラセンでイニシエーションした皮膚腫よう形成を促進する
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Material:
Volume: 24  Issue:Page: 510-514  Publication year: May. 01, 2001 
JST Material Number: S0989A  ISSN: 0918-6158  CODEN: BPBLEO  Document type: Article
Article type: 原著論文  Country of issue: Japan (JPN)  Language: ENGLISH (EN)
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Organo As,Sb,Bi,Ge compounds  ,  Carcinogenic mechanisms and factors  ,  Toxicity of organic compounds 
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Reference (28):
  • 1) IARC, “IARC Monographs on the Evaluation of Carcinogenic Risks to Humans; Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs,” Vol. 1 to 42, IARC, Lyon, 1987, pp. 100-106.
  • 2) Vahter M.E., “Biological Monitoring of Toxic Metals,” ed. by Clarkson T.W., Friberg L., Nordberg G.F., Sager P.R., Plenum Press, New York, 1988, pp. 303-321.
  • 3) National Research Council (NRC), “Report: Arsenic in Drinking Water,” National Academy Press, Washington, D.C., 1999.
  • 4) Okada S., Yamanaka K., “Induction of Lung-specific DNA Damage by Methylarsenics via the Production of Free Radicals, In: Nriagu J.O. (ed.), Arsenic in the Environment. Part II: Human Health and Ecosystem Effects,” John Wiley & Sons, New York, 1994, pp. 143-157.
  • 5) Yamanaka K., Ohtsubo K., Hasegawa A., Hayashi H., Ohji H., Kanisawa M., Okada S., Carcinogenesis, 17, 767-770 (1996).
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