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J-GLOBAL ID：200902108682404830   Reference number：03A0368367

Sensitive Detection of LOH Events in a Human Cell Line after C-ion Beam Exposure.

Cイオンビーム照射後のヒト細胞株のLOH事象の高感度検出

Author (3)： MORIMOTO S (Inst. Physical and Chemical Res.(RIKEN), Saitama, JPN) ,  HONMA M (National Inst. Health Sci., Tokyo, JPN) ,  YATAGAI F (Inst. Physical and Chemical Res.(RIKEN), Saitama, JPN)
Material： Journal of Radiation Research  (J Radiat Res)
Volume： 43  Issue： Supplement  Page： S163-S167  Publication year： Dec. 2002 
JST Material Number： F0337A  ISSN： 0449-3060  CODEN： JRARAX  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cultured cell ,...
Semi thesaurus term： TK6-20C細胞

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JST classification (2)： Influence on cellular levels  (EK02030D) ,  Genetic variation  (EC01030Y)

Reference (17)：

• GOODHEAD, D. T. Initial events in the cellular effects of ionizing radiations : clustered damage in DNA. Int. J. Radiat. Biol. 1994, 65, 7-17
• WARD, J. F. Radiation mutagenesis : the initial DNA lesions responsible. Radiat. Res. 1995, 142, 362-368
• HONMA, M. Illegitimate recombination leading to allelic loss and unbalanced translocation in p53-mutated human lymphoblastoid cells. Mol. Cell. Biol. 1997, 17, 4774-4781
• GROSOVSKY, A. J. DNA-sequence specificity of mutations at the human thymidine kinase locus. Mutat. Res. 1993, 289, 231-243
• GIVER, C. R. Mutational spectrum of X-ray induced TK^- human cell mutants. Carcinogenesis. 1995, 16, 267-275

Terms in the title (5)： イオンビーム照射 ,  ヒト細胞株 ,  LOH ,  事象 ,  高感度