Art

J-GLOBAL ID：200902116097528160   Reference number：01A0702707

Pentalenolactone I and Hygromycin A, Immunosuppressants produced by Streptomyces filipinensis and Streptomyces hygroscopicus.

Streptomyces filipinensisおよびStreptomyces hygroscopicusが産生する免疫抑制物質,Pentalenolactone IおよびHygromycin Aについて

Author (4)： UYEDA M (Kumamoto Univ., Kumamoto, JPN) ,  MIZUKAMI M (Kumamoto Univ., Kumamoto, JPN) ,  YOKOMIZO K (Kumamoto Univ., Kumamoto, JPN) ,  SUZUKI K (Kumamoto Univ., Kumamoto, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 65  Issue： 5  Page： 1252-1254  Publication year： May. 23, 2001 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Streptomyces hygroscopicus ,...
Semi thesaurus term： Streptomyces ,...

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JST classification (2)： Microorganism biochemistry  (EG03020N) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D)

Substance index (5)： Ciclosporin ,  Tacrolimus ,  Hygromycin ,  Thymidine ,  Pentalenolactone A

Reference (13)：

• 1) Borel, J.F., Feurer, C., Magnee, C., and Stehelin, H., Effects of the new anti-lymphocytic peptide cyclosporin A in animals. Immunology, 32, 1017-1025 (1977).
• 2) Kino, T., Hatanaka, H., Hashimoto, M., Nishiyama, M., Goto, T., Okuhara, M., Kohsaka, M., Aoki., H., and Imanaka, H., FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J. Antibiot., 40, 1249-1255 (1987).
• 3) Sakamoto, K., Izumi, S., Miyauchi, M., and Okuhara, M., A new assay method for immunosuppressants with a tacrolimus (FK506)-like mode of action. J. Antibiot., 48, 727-729 (1995).
• 4) Izumi, S., Ueda, H., Okumura, M., Aoki, H., and Yamamura, Y., Effect of Nocardia rubra cell wall skeleton on murine interferon production in vitro. Cancer Res., 46, 1960-1965 (1986).
• 5) Shirling, E.B. and Gottlieb, D., Methods for characterization of Streptomyces species. Int. Syst. Bacteriol., 16, 313-340 (1966).

Terms in the title (2)： Streptomyces ,  免疫抑制物質