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J-GLOBAL ID：200902119589278665   Reference number：99A0662194

Conformation of the Primary Binding Loop Folded through an Intramolecular Interaction Contributes to the Strong Chymotrypsin Inhibitory Activity of the Chymotrypsin Inhibitor from Erythrina variegata Seeds.

分子内相互作用により折り畳まれた1次結合ループの立体配座がErythrina variegataの種子由来のキモトリプシン阻害物質の強力なキモトリプシン阻害活性に寄与している

Author (6)： IWANAGA S (Kyushu Univ., Fukuoka) ,  NAGATA R (Kyushu Univ., Fukuoka) ,  MIYAMOTO A (Kyushu Univ., Fukuoka) ,  KOUZUMA Y (Kyushu Univ., Fukuoka) ,  YAMASAKI N (Kyushu Univ., Fukuoka) ,  KIMURA M (Kyushu Univ., Fukuoka)
Material： Journal of Biochemistry  (J Biochem)
Volume： 126  Issue： 1  Page： 162-167  Publication year： Jul. 01, 1999 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： intramolecular interaction ,...
Semi thesaurus term： Erythrina variegata

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JST classification (2)： Enzyme in general  (EB09010D) ,  Biological function  (EB03040U)

Reference (24)：

• JOUBERT, F. J. Purifica-tion and some properties of two proteinase inhibitors (DE-1 and DE-3) from Erythrina latissima (vroad-eaved Erythrina) seeds. Hoppe-Seyler's Z. Physiol. Chem. 1981, 362, 531-538
• JOUBERT, F. J. Purification and properties of the proteinase inhibitors from Erythrina caffra (coast Erythrina) seeds. Int. J. Biochem. 1982, 14, 187-193
• KOUZUMA, Y. Isolation and primary structure of proteinase inhibitors from Erythrina variegata (LINN) var. Orientalis seeds. Biosci Biotech. Biochem. 1992, 56, 1819-1824
• KIMURA, M. Amino acid sequence of chymotrypsin inhibitor ECI from the seeds of Erythrina variegata (LINN) var. orientalis. Biosci. Biotech. Biochem. 1993, 57, 102-106
• NAKAGAKI, T. Inhibitory potecy of Erythrina variegata proteinase inhibitors toward serine proteinases in the blood coagulation and fibrinolytic systems. Biosci. Biotech. Biochem. 1996, 60, 1383-1385

Terms in the title (8)： 分子内相互作用 ,  ループ ,  立体配座 ,  Erythrina ,  種子 ,  キモトリプシン阻害物質 ,  キモトリプシン ,  阻害活性