Art

J-GLOBAL ID：200902128202171433   Reference number：98A0257856

Synthesis of a New Phospholipase A₂ Inhibitor of an Aldehyde Terpenoid and its Possible Inhibitory Mechanism.

アルデヒドテルペノイド系新規ホスホリパーゼA₂阻害剤の合成及びその推定阻害機構

Author (8)： TANAKA K (Kwansei Gakuin Univ., Nishinomiya, JPN) ,  KAMATANI M (Kwansei Gakuin Univ., Nishinomiya, JPN) ,  MORI H (Kwansei Gakuin Univ., Nishinomiya, JPN) ,  FUJII S (Kwansei Gakuin Univ., Nishinomiya, JPN) ,  IKEDA K (Osaka Univ. Pharmaceutical Sci., Takatsuki, JPN) ,  HISADA M (Suntory Inst. Bioorganic Res., Osaka, JPN) ,  ITAGAKI Y (Suntory Inst. Bioorganic Res., Osaka, JPN) ,  KATSUMURA S (Kwansei Gakuin Univ., Nishinomiya, JPN)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 39  Issue： 10  Page： 1185-1188  Publication year： Mar. 05, 1998 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *terpenoid ,...
Semi thesaurus term： ionone ,...

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JST classification (2)： Diterpenes,sesterterpenes  (CF10023R) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (7)： β-Ionone ,  (4E)-5-(2,6,6-Trimethyl-1-cyclohexenyl)-4-penten-2-yn-1-ol ,  (E)-2-[(E)-2-(2,6,6-Trimethyl-1-cyclohexenyl)vinyl]-4-hydroxy-2-butenoic acid ,  (E)-2-[(E)-2-(2,6,6-Trimethyl-1-cyclohexenyl)vinyl]-4-oxo-2-butenoic acid methyl ester ,  (3E)-2-[(E)-2-Oxoethylidene]-4-[[(8aS)-2,5,5,8aβ-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen]-1-yl]-3-butenoic acid methyl ester ,  (3E)-2-[(E)-2-Oxoethylidene]-6-methyl-3,5-heptadienoic acid methyl ester ,  (3E,5E)-2-[(E)-2-Oxoethylidene]-6,10-dimethyl-3,5,9-undecatrienoic acid methyl ester

Terms in the title (4)： ホスホリパーゼA2 ,  阻害剤 ,  推定 ,  阻害