Art

J-GLOBAL ID：200902131115676783   Reference number：03A0017562

Synthesis of the acyl side chain segment of polyoxypeptins using regioselective ring-opening of chiral 2,3-epoxy alcohol.

2,3-エポキシアルコールの位置特異性開環を用いたポリオキシペプチンAおよびBのアシル側鎖セグメントの合成

Author (5)： MAKINO K (Chiba Univ., Chiba, JPN) ,  SUZUKI T (Chiba Univ., Chiba, JPN) ,  AWANE S (Chiba Univ., Chiba, JPN) ,  HARA O (Chiba Univ., Chiba, JPN) ,  HAMADA Y (Chiba Univ., Chiba, JPN)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 43  Issue： 51  Page： 9391-9395  Publication year： Dec. 16, 2002 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...
Semi thesaurus term： Wittig reaction ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=03A0017562&from=J-GLOBAL&jstjournalNo=E0366A") }}

JST classification (2)： Pyranes  (CF07092R) ,  Synthesis of antibiotics  (GX04000Z)

Substance index (16)： Polyoxypeptin A ,  Polyoxypeptin B ,  (αS,2R)-α,2-Dihydroxy-α-methyl-5α-[(S)-2-methylbutyl]-6β-ethyltetrahydro-2H-pyran-2β-acetic acid benzyl ester ,  (2S)-2-Hydroxy-2-methyl-3-oxobutanoic acid benzyl ester ,  (2R,3R)-2,3-Epoxypentan-1-ol ,  2-Pentyn-1-ol ,  (E)-2-Penten-1-ol ,  (2S,3R)-2-Isopropyl-1,3-pentanediol ,  (2S,3R)-3-Ethyl-5-methyl-1,2-hexanediol ,  [(S)-2-Methylbutyl]bromomagnesium ,  (2R,4S)-2-[(R)-1-(tert-Butyldimethylsiloxy)propyl]-4-methylhexanal ,  (4R,6S)-4-[(R)-1-(tert-Butyldimethylsiloxy)propyl]-6-methyl-2-octenoic acid ethyl ester ,  (4R,6S)-4-[(R)-1-(tert-Butyldimethylsiloxy)propyl]-6-methyloctanal ,  (6R,8S)-2,8-Dimethyl-6-[(R)-1-(tert-butyldimethylsiloxy)propyl]-2-decenoic acid benzyl ester ,  (2S,3R,6R,8S)-2,3-Dihydroxy-2,8-dimethyl-6-[(R)-1-(tert-butyldimethylsiloxy)propyl]decanoic acid benzyl ester ,  (2S,6R,8S)-2,8-Dimethyl-2-hydroxy-3-oxo-6-[(R)-1-(tert-butyldimethylsiloxy)propyl]decanoic acid benzyl ester

Terms in the title (5)： 位置特異性 ,  開環 ,  ポリオキシペプチンA ,  側鎖 ,  セグメント