Art

J-GLOBAL ID：200902132840496061   Reference number：02A0591251

The Nitric Oxide Donor NOC12 Protects Cultured Astrocytes Against Apoptosis via a cGMP-Dependent Mechanism.

一酸化窒素供与体NOC12はcGMP依存性機序により培養星状細胞をアポトーシスから保護する

Author (7)： TAKUMA K (Kobe Gakuin Univ., Kobe, JPN) ,  PHUAGPHONG P (Osaka Univ., Osaka, JPN) ,  LEE E (Kobe Gakuin Univ., Kobe, JPN) ,  ENOMOTO R (Kobe Gakuin Univ., Kobe, JPN) ,  MORI K (Kobe Gakuin Univ., Kobe, JPN) ,  BABA A (Osaka Univ., Osaka, JPN) ,  MATSUDA T (Osaka Univ., Osaka, JPN)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 89  Issue： 1  Page： 64-71  Publication year： May. 01, 2002 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *polyazene ,...
Semi thesaurus term： 一酸化窒素供与体 ,...

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JST classification (3)： Basic research of other drugs acting on metabolism  (GW13060I) ,  Basic neurology  (GN01020W) ,  Cell physiology in general  (EF02010S)

Substance index (7)： cGMP ,  MTT ,  3-[2-(Ethylamino)ethyl]-3-ethyltriazene-1-ol 2-oxide ,  YC-1 ,  KT-5823 ,  ODQ ,  NOC-12

Reference (40)：

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• 2 Nomura Y and Kitamura Y: Inducible nitric oxide synthase in glial cells. Neurosci Res 19, 103 – 107 (1993)
• 3 Schuman EM and Madison DV: Nitric oxide and synaptic function. Annu Rev Neurosci 17, 153 – 183 (1994)
• 4 Bredt DS and Snyder SH: Transient nitric oxide synthase neurons in embryonic cerebral cortical plate, sensory ganglia, and olfactory epithelium. Neuron 13, 301 – 313 (1994)
• 5 Uehara T, Kikuchi Y and Nomura Y: Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells. J Neurochem 72, 196 – 205 (1999)

Terms in the title (6)： 一酸化窒素供与体 ,  cGMP ,  依存性 ,  培養 ,  星状細胞 ,  アポトーシス