Art

J-GLOBAL ID：200902137803667419   Reference number：95A0298040

Alteration of Ammonia and Carnitine Levels in Short-Term Treatment with Pivalic Acid-Containing Prodrug.

ピバル酸含有プロドラッグでの短期間治療におけるアンモニアとカルニチン量の変化

Author (8)： ITO T (Nagoya City Univ. Medical School, Nagoya) ,  SUGIYAMA N (Nagoya City Univ. Medical School, Nagoya) ,  KOBAYASHI M (Nagoya City Univ. Medical School, Nagoya) ,  KIDOUCHI K (Nagoya City Higashi General Hospital, Nagoya) ,  ITOH T (Nagoya City Midori General Hospital, Nagoya) ,  UEMURA O (Nagoya Daini Red Cross Hospital, Nagoya) ,  SUGIYAMA K (Nagoya City Univ. Medical School, Nagoya) ,  TOGARI H (Nagoya City Univ. Medical School, Nagoya)
Material： Tohoku Journal of Experimental Medicine  (Tohoku J Exp Med)
Volume： 175  Issue： 1  Page： 43-53  Publication year： Jan. 1995 
JST Material Number： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： セフテラムピボキシル ,...

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JST classification (1)： Clinical application of antibiotics acting on pathogenic organisms  (GX05030N)

Substance index (3)： Cefteram pivoxil ,  Carnitine ,  Glutamine

Reference (26)：

• 1) Böhles, H., Richter, K., Wagner-Thiessen, E. & Schäfer, H. (1982) Decreased serum carnitine in valproate induced Reye syndrome. Eur. J. Pediatr., 139, 185-186.
• 2) Brusilow, S.W. & Horwich, A.L. (1989) Urea cycle enzymes. In: The Metabolic Basis of Inherited Disease, edited by C.R. Scriver, A.L. Beaudet, W.S. Sly & D. Valle, McGraw-Hill, New York, pp. 629-663.
• 3) Coude, F.X., Rabier, D., Cathelineau, L., Grimber, G., Parvy, P. & Kamoun, P.P. (1981) Letter to the editor: A mechanism for valproate-induced hyperammonemia. Pediatr. Res., 15, 974-975.
• 4) Coude, F.X., Grimber, G., Parvy, P., Rabier, D. & Petit, F. (1983) Inhibition of ureagenesis by valproate in rat hepatocytes. Biochem. J, 216, 233-236.
• 5) Deyl, Z., Hyanek, J. & Horakova, M. (1986) Profiling of amino acids in body fluids and tissues by means of liquid chromatography. J. Chromatogr., 379, 177-250.

Terms in the title (6)： ピバル酸 ,  プロドラッグ ,  短期間 ,  治療 ,  アンモニア ,  カルニチン