Art

J-GLOBAL ID：200902141970087820   Reference number：97A0203030

New Antitumor Substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465.

新規抗腫よう物質FR901463,FR901464とFR901465 3 FR901463,FR901464とFR901465の構造

Author (4)： NAKAJIMA H (Fujisawa Pharmaceutical Co., Ltd., Ibaraki, JPN) ,  TAKASE S (Fujisawa Pharmaceutical Co., Ltd., Ibaraki, JPN) ,  TERANO H (Fujisawa Pharmaceutical Co., Ltd., Ibaraki, JPN) ,  TANAKA H (Fujisawa Pharmaceutical Co., Ltd., Ibaraki, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 50  Issue： 1  Page： 96-99  Publication year： Jan. 1997 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Pseudomonas ,...
Semi thesaurus term： FR-901463 ,...

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JST classification (1)： Antibiotic fermentation  (GX03000S)

Substance index (3)： WB-2663A ,  FR-901464 ,  WB-2663C

Reference (5)：

• 1) NAKAJIMA, H.; B. SATO, T. FUJITA, S. TAKASE, H, TERANO & M. OKUHARA: New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J. Antibiotics 49: 1196-1203, 1996
• 2) NAKAJIMA, H.; Y. HORI, H. TERANO, M. OKUHARA, T. MANDA, S. MATSUMOTO & K. SHIMOMURA: New antitumor substances, FR901463, FR901464 and FR901465. II. Antitumor activities on experimental tumors in mice and mechanism of action. J. Antibiotics 49: 1204-1211, 1996
• 3) WERNER, G.; H. HAGENMAIER, H. DRAUTZ, A. BAUMGART-NER & H. ZAHNER: Metabolic products of microorganisms. 224 Bafilomycins, a new group of macrolide antibiotics. Production, isolation, chemical structure and biological activity. J. Antibiotics 37: 110-117, 1984
• 4) BREITMAIER, E. & W. VOELTER: Carbon-13 NMR spectroscopy. p. 193, VCH, New York, 1987
• 5) BLOCK, R. & L. GILBERT: Synthsis of both enantiomers of γ-substituted α,β-unsaturated γ-lactones. J. Org. Chem. 52:4603-4605,1987

Terms in the title (1)： 抗腫よう物質