Art

J-GLOBAL ID：200902145804225978   Reference number：98A0527532

Regulation of Promoter and Intron Enhancer Activity in Immunoglobulin Heavy-Chain Genes during B-Cell Differentiation.

B-細胞分化の間のイムノグロブリン重鎖遺伝子におけるプロモータとイントロンエンハンサ活性の調節

Author (3)： NAITO A (Sci. Univ. Tokyo, Chiba, JPN) ,  SUZUKI Y (Osaka Prefectural Inst. Public Health, Osaka, JPN) ,  AZUMA T (Sci. Univ. Tokyo, Chiba, JPN)
Material： Microbiology and Immunology  (Microbiol Immunol)
Volume： 42  Issue： 5  Page： 399-405  Publication year： May. 1998 
JST Material Number： F0715A  ISSN： 0385-5600  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： transgenic mouse ,...
Semi thesaurus term： *B lymphocyte ,...

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JST classification (2)： Leukocytes,lymphocytes  (EJ03030H) ,  Biochemistry of antigens,antibodies,complements  (ED04020L)

Reference (31)：

• 1) Alt, F.W., Yacopolus, G.D., Blackwell, T.K., Wood, C., Thomas, E., and Baltimore, D. 1984. Ordered rearrangement of immunoglobulin heavy chain variable region segments. EMBO J. 3: 1209-1219.
• 2) Andersson, J., Sjoberg, O., and Moller, G. 1972. Induction of immunoglobulin synthesis in vitro by lipopolysaccharides. Eur. J. Immunol. 2: 349-353.
• 3) Azuma, T., Motoyama, N., Fields, L.E., and Loh, Y.D. 1993. Mutation of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer. Int. Immunol. 5: 121-130.
• 4) Calame, K., and Ghosh, S. 1995. Regulation of immunoglobulin gene transcription, p. 397-422. In Honjo, T., and Alt, F.W. (eds), Immunoglobulin genes, Second ed, Academic Press, New York.
• 5) Chen, U., Scheuermann, R.H., Wirth, T., Gerster, T., Roeder, R.G., Harshman, K., and Berger, C. 1991. Anti-IgM antibodies down modulate mu-enhancer activity and OTF2 levels in LPS-stimulated mouse splenic B-cells. Nucleic Acids Res. 19: 5981-5989.

Terms in the title (7)： 細胞分化 ,  イムノグロブリン ,  重鎖 ,  遺伝子 ,  プロモータ ,  活性 ,  調節