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J-GLOBAL ID：200902150632299625   Reference number：00A0728855

Enzymatic Conversion of Cyclic Dipeptides to Dehydro Derivatives That Inhibit Cell Division.

環状ジペプチドから細胞分裂阻害活性を示す脱水素体への酵素変換

Author (4)： KANZAKI H (Okayama Univ., Okayama, JPN) ,  IMURA D (Okayama Univ., Okayama, JPN) ,  NITODA T (Okayama Univ., Okayama, JPN) ,  KAWAZU K (Okayama Univ., Okayama, JPN)
Material： Journal of Bioscience and Bioengineering  (J Biosci Bioeng)
Volume： 90  Issue： 1  Page： 86-89  Publication year： Jul. 25, 2000 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *dipeptide ,...
Semi thesaurus term： Streptomyces albulus ,...

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JST classification (1)： Applications of enzymes  (EB09100B)

Substance index (4)： Diketopiperazine ,  (3Z,6S)-3-Benzylidene-6-methyl-2,5-piperazinedione ,  (3Z)-3-Benzylidene-2,5-piperazinedione ,  (3Z,6Z)-3,6-Dibenzylidene-2,5-piperazinedione

Reference (13)：

• 1. Sammes, P.G.: Naturally occurring 2,5-diketopiperazines and related compounds. Fortschr. Chem. Org. Naturst., 32, 51-118 (1975).
• 2. Prasad, C.: Bioactive cyclic dipeptides. Peptides, 1, 151-164 (1995).
• 3. Kobayashi, A., Ooe, K., Yata, S., and Kawazu, K.: Chemical studies of microtubule assembly regulators of microbial origin. Tennen Yuki Kagobutsu Toronkai Koen Yoshishu, 31, 388-395 (1989).
• 4. Kanzaki, H., Imura, D., Sashida, R., Kobayashi, A., and Kawazu, K.: Effective production of a dehydro cyclic dipeptide albonoursin with pronuclear fusion inhibitory activity. I. Taxonomy of producing strain and fermentation. J. Antibiot., 52, 1017-1022 (1999).
• 5. Kanzaki, H., Imura, D., Nitoda, T., and Kawazu, K.: Effective production of a dehydro cyclic dipeptide albonoursin with pronuclear fusion inhibitory activity. II. Biosynthetic and bioconversion studies. J. Antibiot., 53, 58-62 (2000).

Terms in the title (6)： 環状ジペプチド ,  細胞分裂 ,  阻害活性 ,  脱水 ,  素体 ,  酵素