Art

J-GLOBAL ID：200902157594759522   Reference number：02A0124896

Doxorubicin Affects the Cardiac Muscarinic System in the Rat.

ラット心臓におけるドキソルビシンのムスカリン作動性神経系への影響

Author (8)： CHUGUN A (Kitasato Univ., Towada-shi, JPN) ,  UCHIDE T (Kitasato Univ., Towada-shi, JPN) ,  TEMMA K (Kitasato Univ., Towada-shi, JPN) ,  KENNEDY R H (Univ. Arkansas for Medical Sci., AR, USA) ,  KLIMBERG S V (Univ. Arkansas for Medical Sci., AR, USA) ,  HARA Y (Kitasato Univ., Towada-shi, JPN) ,  SASAKI T (Kitasato Univ., Towada-shi, JPN) ,  AKERA T (Merck Sharp and Dohm Res. Lab. Japan, Tokyo, JPN)
Material： Journal of Veterinary Medical Science  (日本獣医学会会誌)
Volume： 63  Issue： 12  Page： 1315-1322  Publication year： Dec. 25, 2001 
JST Material Number： F0905A  ISSN： 0916-7250  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antineoplastic antibiotics ,...
Semi thesaurus term： cellular signal transduction ,...

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JST classification (2)： Heart  (EJ04020D) ,  Basic research of parasympathetics  (GW05032S)

Substance index (4)： Doxorubicin ,  Carbachol ,  R-PIA ,  Quinuclidinyl benzilate

Reference (33)：

• 1. Benjamin, R. S., Riggs C. E. Jr. and Bachur, N. R. 1977. Plasma pharmacokinetics of adriamycin and metabolites in humans with normal hepatic and renal function. Cancer Res. 37: 1416-1424.
• 2. Boom, F. E. 1990. Drugs acting on the central nervous system. pp 244-268. In: Goodman and Gilman's The Pharmacological Bases of Therapeutics (Gilman, A. G., Rall, T. W., Nies, A. S. and T. Palmer eds.), Pergamon Press, New York.
• 3. Brenner, D. E., Galloway, S., Cooper, J., Noone, R. and Hande, K. R. 1985. Improved high-performance liquid chromatography assay of doxorubicin: detection of circulating aglycones in human plasma and comparison with thin-layer chromatography. Cancer Chemother. Pharmacol. 14: 139-145.
• 4. Bristow, M. R., Sageman, W. S., Scott, R. H., Billingham, M. E., Bowden, R. E., Kernoff, R. S., Snidow, G. H. and Daniels, J. R. 1980. Acute and chronic cardiovascular effects of doxorubicin in the dog: the cardiovascular pharmacology of drug-induced histamine release. J. Cardiovasc. Pharmacol. 2: 487-515.
• 5. Brown, K. A., Blow, A. J., Wess R. M. and Stewart J. A. 1989. Acute effects of doxorubicin on human left ventricular systolic and diastolic function. Am. Heart J. 118: 979-982

Terms in the title (5)： ラット ,  心臓 ,  ドキソルビシン ,  ムスカリン ,  神経系