Art

J-GLOBAL ID：200902158382776989   Reference number：00A0757468

Protection Against the Diabetogenic Effect of Feeding tert-Butylhydroquinone to Rats Prior to the Administration of Streptozotocin.

tert-ブチルヒドロキノンを含む食事をあらかじめ摂取したラットではストレプトゾトシン依存性糖尿病の発症は軽減される

Author (4)： NISHIZONO S (Kyushu Univ., Fukuoka, JPN) ,  HAYAMI T (Kyushu Univ., Fukuoka, JPN) ,  IKEDA I (Kyushu Univ., Fukuoka, JPN) ,  IMAIZUMI K (Kyushu Univ., Fukuoka, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 64  Issue： 6  Page： 1153-1158  Publication year： Jun. 23, 2000 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： polyphenol ,...
Semi thesaurus term： insulin ,...

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JST classification (1)： Basic research of drugs acting on carbohydrate metabolism  (GW13020Q)

Substance index (2)： tert-Butylhydroquinone ,  Curcumin

Reference (25)：

• 1) Freeman, B. A., and Crapo, J. D., Biology of disease: Free radicals and tissue injury. Lab. Invest., 47, 412-426 (1982).
• 2) Rabinovitch, A., Suarez, W. L., Thomas, P. D., Strynadka K., and Simpson, I., Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation. Diabetologia, 35, 409-413 (1992).
• 3) Porte Jr., D. and Schwartz, M. W., Diabetes complications: why is glucose potentially toxic? Science, 272, 699-700 (1996).
• 4) Sumoski, W., Baquerizo, H., and Rabinovitch, A. Oxygen free radical scavengers protect rat islet cells from damage by cytokines. Diabetologia, 32, 792-796 (1989).
• 5) Stephens, N. G., Parsons, A., Schofield, P. M., Kelly, F., Cheeseman, K., and Mitchinson, M. J., Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet, 347, 781-786 (1996).

Terms in the title (7)： tert-ブチルヒドロキノン ,  食事 ,  ラット ,  ストレプトゾトシン ,  依存性 ,  糖尿病 ,  発症