Art

J-GLOBAL ID：200902166160434624   Reference number：02A0909271

New Zinc(II) Complexes with Tetradentate Amino Acid Derivatives: Structure Characterization, Solution Chemistry, and in vitro Insulinomimetic Activity.

四座配位アミノ酸誘導体による新しい亜鉛(II)錯体 構造キャラクタリゼーション,溶液化学,およびin vitroインシュリン様活性

Author (8)： YOSHIKAWA Y (Osaka City Univ., Osaka) ,  KAWABE K (Osaka City Univ., Osaka) ,  TADOKORO M (Osaka City Univ., Osaka) ,  SUZUKI Y (Teikyo Univ., Utsunomiya) ,  YANAGIHARA N (Teikyo Univ., Utsunomiya) ,  NAKAYAMA A (Kyoto Pharmaceutical Univ., Kyoto) ,  SAKURAI H (Kyoto Pharmaceutical Univ., Kyoto) ,  KOJIMA Y (Osaka City Univ., Osaka)
Material： Bulletin of the Chemical Society of Japan  (Bull Chem Soc Jpn)
Volume： 75  Issue： 11  Page： 2423-2432  Publication year： Nov. 15, 2002 
JST Material Number： G0450A  ISSN： 0009-2673  CODEN： BCSJA8  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *zinc complex ,...
Semi thesaurus term： stability constant

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JST classification (4)： Complexes of 9 and 10 groups  (CE01050Y) ,  Amino acids  (CF10070V) ,  Crystal structure of complex of transition metals(excluding iron group)  (BK09030X) ,  Enzyme in general  (EB09010D)

Substance index (24)： N-(2-Pyridylmethyl)aspartic acid dimethyl ester ,  N-(2-Pyridylmethyl)aspartic acid ,  N-(6-Methyl-2-pyridylmethyl)aspartic acid dimethyl ester ,  N-(6-Methyl-2-pyridylmethyl)aspartic acid ,  N^α-(2-Pyridylmethyl)histidine methyl ester ,  N^α-(2-Pyridylmethyl)histidine ,  N^α-[2-[[(1S)-1-(Methoxycarbonyl)-2-methylpropyl]amino]ethyl]histidine methyl ester ,  N^α-[2-[[(1S)-1-Carboxy-2-methylpropyl]amino]ethyl]histidine ,  N^α-[2-[[(1S,2R)-1-Carboxy-2-hydroxypropyl]amino]ethyl]histidine ,  N^α-[2-[[(1S,2R)-1-(Methoxycarbonyl)-2-hydroxypropyl]amino]ethyl]histidine methyl ester ,  N,N-Bis(2-pyridylmethyl)glycine methyl ester ,  Bis(2-pyridinylmethyl)aminoacetic acid ,  N,N-Bis(2-pyridylmethyl)alanine methyl ester ,  N,N-Bis(2-pyridylmethyl)alanine ,  N,N-Bis(2-pyridylmethyl)valine methyl ester ,  N,N-Bis(2-pyridylmethyl)valine ,  N,N-Bis(2-pyridylmethyl)leucine methyl ester ,  N,N-Bis(2-pyridylmethyl)leucine ,  N,N-Bis(2-pyridylmethyl)homoserine methyl ester ,  N,N-Bis(2-pyridylmethyl)homoserine ,  N,N-Bis(2-pyridylmethyl)aspartic acid dimethyl ester ,  N,N-Bis(2-pyridylmethyl)aspartic acid ,  N,N-Bis(2-pyridylmethyl)-D-valine methyl ester ,  N,N-Bis(2-pyridylmethyl)-D-valine

Reference (20)：

• 1) S. J. Lippard and J. M. Berg, “Principles of Bioinorganic Chemistry,” University Science Books, California (1994);
•  J. J. R. Fransto de Silva and R. J. P. Williams “The Biological Chemistry of the Elements,” Clarendon Press, Oxford (1993);
•  J. A. Cowan, “Inorganic Biochemistry: An Introduction,” 2nd ed, Wiley-VCH (1997).
• 2) A. B. Fujii, R. A. DiSilvestro, D. Frid, C. Katz, and W. Malarkey, Am. J. Clin. Nutr., 66, 639 (1997).
• 3) L. Coulston and P. Dandona, Diabetes, 29, 665 (1980).

Terms in the title (7)： アミノ酸誘導体 ,  亜鉛 ,  錯体 ,  キャラクタリゼーション ,  溶液化学 ,  インシュリン ,  活性