Art

J-GLOBAL ID：200902168701053559   Reference number：95A0625804

Cremeomycin, a Novel Cytotoxic Antibiotic from Streptomyces cremeus. Structure Elucidation and Biological Activity.

クレメオマイシン,Streptomyces cremeusからの新規の細胞毒性抗生物質 構造解析と生物活性

Author (3)： MCGUIRE J N (Univ. Illinois at Urbana-Champaign, IL, USA) ,  WILSON S R (Univ. Illinois at Urbana-Champaign, IL, USA) ,  RINEHART K L (Univ. Illinois at Urbana-Champaign, IL, USA)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 48  Issue： 6  Page： 516-519  Publication year： Jun. 1995 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： antibiotics fermentation ,...
Semi thesaurus term： Streptomyces ,...

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JST classification (2)： Antibiotic fermentation  (GX03000S) ,  Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y)

Substance index (1)： Cremeomycin

Reference (20)：

• EHRLICH, J. 6-Diazo-5-oxo-L-norleucine, a new tumor inhibitory substance. Antibiotics & Chemotherapy. 1956, 6, 487
• EHRLICH, J. Antibiotic studies of azaserine. Nature. 1954, 173, 72
• LUKENBACH, E. L. Studies on the synthesis and biosynthesis of alazopeptin. Ph.D.Thesis, University of Illinois. 1971
• PITTILLO, R. F. Azaserine and 6-diazo-5-oxo L-norleucine (DON). Antibiotics I.Mechanism of Action. 1967, 481-493
• LEE, M. D. New antitumor antibiotic, LL-D0513β.Fermentation, isolation, structure determination and biological activities. J.Antibiotics. 1987, 40, 1657-1663

Terms in the title (6)： クレメオマイシン ,  Streptomyces ,  細胞毒性 ,  抗生物質 ,  構造解析 ,  生物活性