Art

J-GLOBAL ID：200902173264689132   Reference number：01A0833414

Potent Antimalarial Activities of Polyether Antibiotic, X-206.

強力な抗マラリア活性を示すポリエーテル抗生物質,X-206

Author (8)： OTOGURO K (Kitasato Inst., Tokyo, JPN) ,  KOHANA A (Kitasato Inst., Tokyo, JPN) ,  MANABE C (Kitasato Inst., Tokyo, JPN) ,  ISHIYAMA A (Kitasato Inst., Tokyo, JPN) ,  UI H (Kitasato Inst., Tokyo, JPN) ,  SHIOMI K (Kitasato Inst., Tokyo, JPN) ,  YAMADA H (Kitasato Inst., Tokyo, JPN) ,  OMURA S (Kitasato Inst., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 54  Issue： 8  Page： 658-663  Publication year： Aug. 25, 2001 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antibiotics ,...
Semi thesaurus term： X-206 ,...

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JST classification (1)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C)

Substance index (2)： X-206 ,  Octacyclomycin

Reference (18)：

• 1) NUSSENZWEIG, R. & F. ZAVALA: A malaria vaccine based on a sporozoite antigen, N. Engl. J. Med. 336: 128-130, 1997
• 2) BERGER, J.; A. I. RACHLIN, W E. SCOTT, L. H. STERNBACH & M. W. GOLDBERG: The isolation of three new crystalline antibiotics from Streptomyces. J. Am. Chem. Soc. 73: 5295-5298, 1951
• 3) GUMILA, C.; M. L. ANCELIN, G. JEMINET, A. M. DELORT, G. MIGUEL & H. J. VIAL: Differential in vitro activities of ionophore compounds against Plasmodium falciparum and mammalian cells. Antimicrob. Agents Chemother. 40: 602-608, 1996
• 4) GUMILA, C.; M. L. ANCELIN, A. M. DELORT, G. JEMINET, A. M. DELORT & H. J. VIAL: Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds. Antimicrob. Agents Chemother. 41: 523-529, 1996
• 5) FUNAYAMA, S.; S. NOZOE, C. TRONQUET, Y. ANRAKU, K. KOMIYAMA & S. OMURA: Isolation and structure of a new polyether antibiotic, octacylomycin. J. Antibiotics 45: 1686-1691, 1992

Terms in the title (3)： 抗マラリア活性 ,  ポリエーテル ,  抗生物質