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J-GLOBAL ID：200902178112598460   Reference number：98A0419551

MS-430, a Synthetic Pyrimidine Derivative, Influences the Intracellular Signal Transduction Pathway Leading to Neuronal Differentiation of PC12h Cells.

合成ピリミジン誘導体MS-430は,PC12h細胞の神経細胞分化へ導く細胞内シグナル伝達経路に影響する

Author (6)： IKEUCHI T (Osaka Univ., Osaka) ,  NAKATANI A (Osaka Univ., Osaka) ,  YAMADA M (Osaka Univ., Osaka) ,  ITOKAZU N (Miyazaki Medical Coll., Miyazaki) ,  AWAYA A (Mitsui Pharmaceuticals, Inc., Tokyo) ,  HATANAKA H (Osaka Univ., Osaka)
Material： Journal of Biochemistry  (J Biochem)
Volume： 123  Issue： 3  Page： 423-430  Publication year： Mar. 1998 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： PC12 cell ,...
Semi thesaurus term： nerve cell ,...

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JST classification (2)： Cell physiology in general  (EF02010S) ,  Nervous system in general  (EJ12010J)

Substance index (1)： MS-430

Reference (44)：

• GREENE, L. A. The nerve growth factor: biochemistry. Synthesis, and mechanism of action. Annu. rev. Neurosci. 1980, 3, 353-402
• THOENEN, H. the changing scene of neurotrophic factors. Trends Neurosci. 1991, 14, 165-170
• CHAO, M. V. Growth factor signaling: where is the specificity?. Cell. 1992, 68, 995-997
• SEGAL, R. A. Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci. 1996, 19, 463-489
• CARPENTER, G. J. Epidermal growth factor. Annu. Rev. Biochem. 1979, 48, 193-216

Terms in the title (5)： ピリミジン誘導体 ,  MS-430 ,  PC12h細胞 ,  神経細胞分化 ,  細胞内シグナル伝達経路