Art

J-GLOBAL ID：200902191911423628   Reference number：02A0353623

Cardioprotective Effect of Mexiletine in Acute Myocardial Ischemia. Studies in the Rabbit Closed Chest Ischemia Model.

急性心筋虚血に与えるメキシレチンの心臓保護効果 ウサギ閉鎖胸部虚血モデルにおける研究

Author (9)： INUO K (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  NIWANO S (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  MOROHOSHI Y (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  NAKAYAMA S (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  IKEDA K (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  KOJIMA J (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  SAITO J (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  MASUDA T (Kitasato Univ. School of Medicine, Sagamihara, JPN) ,  IZUMI T (Kitasato Univ. School of Medicine, Sagamihara, JPN)
Material： Circulation Journal  (Circ J)
Volume： 66  Issue： 4  Page： 403-410  Publication year： Apr. 2002 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antiarrhythmic drug ,...
Semi thesaurus term： hare

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=02A0353623&from=J-GLOBAL&jstjournalNo=F0908A") }}

JST classification (2)： Basic medicine on cardiovascular system  (GJ01020K) ,  Basic research of cardioactive drugs  (GW07020N)

Substance index (2)： Mexiletine ,  Glibenclamide

Reference (38)：

• 1. Noma A. ATP-regulated K⁺ channel in cardiac muscle. Nature 1983; 305: 147-148.
• 2. Cook DL, Hales N. Intracellular ATP directly blocks K channels in pancreatic beta-cells. Nature 1984; 31: 271-273.
• 3. Spruce AE, Standen NB, Standfield PR. Voltage-dependent ATP-sensitive potassium channels of skeletal muscle membrane. Nature 1985; 316: 736-738.
• 4. Standen NB, Quayle JM, Davies NW, Brayden JE, Huang Y, Nelson MT. Hyperpolarizing vasodilators active ATP-sensitive K channels in atrial smooth muscle. Science 1989; 245: 177-180.
• 5. Noma A, Shibasaki T. Membrane current through adenosine triphosphate-regulated potassium channels in guinea pig ventricular cells. J Physiol 1985; 363: 463-480.

Terms in the title (10)： 心筋虚血 ,  メキシレチン ,  心臓 ,  保護効果 ,  ウサギ ,  閉鎖 ,  胸部 ,  虚血 ,  モデル ,  研究