Art

J-GLOBAL ID：200902192628394391   Reference number：99A0736880

Synthesis and biological activity of oligomer-model compounds containing units of a key platelet-binding disaccharide of heparin.

ヘパリンの血小板結合のためのキー物質である二糖類ユニットを持つオリゴマモデル化合物の合成と生物学的活性

Author (6)： KOSHIDA S (Osaka Univ., Osaka, JPN) ,  SUDA Y (Osaka Univ., Osaka, JPN) ,  FUKUI Y (Osaka Univ., Osaka, JPN) ,  ORMSBY J (State Univ. New York, NY, USA) ,  SOBEL M (State Univ. New York, NY, USA) ,  KUSUMOTO S (Osaka Univ., Osaka, JPN)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 40  Issue： 31  Page： 5725-5728  Publication year： Jul. 30, 1999 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...
Semi thesaurus term： クラスタ化効果

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JST classification (1)： Oligosaccharides  (CF10053Y)

Substance index (7)： 4-O-[2-(Sulfoamino)-6-O-sulfo-2-deoxy-α-D-glucopyranosyl]-α-L-idopyranuronic acid ,  1-O-(2,2,2-Trichloroacetimidoyl)-2-azido-3-O-benzyl-4-O-allyl-2-deoxy-D-glucopyranose 6-acetate ,  1-O-Methyl-2-O-acetyl-3-O-benzyl-α-L-idopyranuronic acid methyl ester ,  4-O,4′-O-[Ethylenebis[iminocarbonylmethyleneoxy(2-azido-3-O-benzyl-6-O-acetyl-1,2,4-trideoxy-α-D-glucopyranose-4,1-diyl)oxy]]bis(1-O-methyl-2-O-acetyl-3-O-benzyl-α-L-idopyranuronic acid methyl) ester ,  4-O,4′-O-[Ethylenebis[iminocarbonylmethyleneoxy[2-(sodiooxysulfonylamino)-6-O-(sodiooxysulfonyl)-1,2,4-trideoxy-α-D-glucopyranose-4,1-diyl]oxy]]bis[1-O-methyl-2-O-(sodiooxysulfonyl)-α-L-idopyranuronic acid sodium] salt ,  1-O-Methyl-2-O-acetyl-3-O-benzyl-4-O-[2-azido-3-O-benzyl-4-O-[2-[2-[2-O-acetyl-3-O-benzyl-4-O-(2-azido-3-O-benzyl-4-O-methyl-6-O-acetyl-2-deoxy-α-D-glucopyranosyl)-5-(methoxycarbonyl)-5-de(hydroxymethyl)-α-L-idopyranose-1-yloxy]ethylamino]-2-oxoethyl]-6-O-acetyl-2-deoxy-α-D-glucopyranosyl]-α-L-idopyranuronic acid methyl ester ,  1-O-Methyl-2-O-(sodiooxysulfonyl)-4-O-[2-(sodiooxysulfonylamino)-4-O-[2-[2-[2-O-(sodiooxysulfonyl)-4-O-[2-(sodiooxysulfonylamino)-4-O-methyl-6-O-(sodiooxysulfonyl)-2-deoxy-α-D-glucopyranosyl]-5-(sodiooxycarbonyl)-5-de(hydroxymethyl)-α-L-idopyranose-1-yloxy]ethylamino]-2-oxoethyl]-6-O-(sodiooxysulfonyl)-2-deoxy-α-D-glucopyranosyl]-α-L-idopyranuronic acid sodium salt

Terms in the title (8)： ヘパリン ,  血小板 ,  キー ,  物質 ,  二糖類 ,  オリゴマ ,  モデル化合物 ,  生物学的活性