Chlovalicin, a New Cytocidal Antibiotic Produced by Sporothrix sp. FO-4649. I Taxonomy, Fermentation, Isolation and Biological Activities.

HAYASHI M; KIM Y-P; TAKAMATSU S; PREEPRAME S; KOMIYA T; MASUMA R; TANAKA H; KOMIYAMA K; OMURA S

Art

J-GLOBAL ID：200902195560445315 Reference number：96A0705227

Chlovalicin, a New Cytocidal Antibiotic Produced by Sporothrix sp. FO-4649. I Taxonomy, Fermentation, Isolation and Biological Activities.

クロバリシン,Sporothrix sp.FO-4649が生産する殺細胞性新抗生物質 I 分類,発酵,単離と生物活性

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Material：
Volume： 49 Issue： 7 Page： 631-634 Publication year： Jul. 1996
JST Material Number： G0489A ISSN： 0021-8820 Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Basic research of antitumor(=antineoplastic)antibiotics , Antibiotic fermentation

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Reference (17)：

1) BOLLINGER, P.; H.-P. SIGG & H.-P. WEBER: Die struktur vonovalicin. HelveticaChimica Acta. 56: 819-830,1973
2) HARTMANN, G. R.; H. RICHTER, E. M. WEINER & W. ZIMMERMANN: On the mechanism of action of the cytostatic drug anguidine and of the immunosuppressive agent ovalicin, two sesquiterpenes from Fungi. Planta Medica34: 231-252, 1978
3) ALLEY, M. C; D. A. SCUDIERO, A. MONKS, M. L. HURSEY, M. J. CZERWINSKI, D. L. FINE, B. J. ABBOTT, J. G. MAYO, R. H. SHOEMAKER & M. R. BOYD: Feasibility of drug screening with panel of human tumor cell lines using a microculture tetrazolium assay. Cancer Res. 48: 589 - 601, 1988
4) BARRON, G. L.: The genera of hyphomycetes from soil. The Williams & Wilkins Co.: 284-285, 1968
5) ARX, J. A. V.: The genera of fungi-sporulating in pure culture (3rd. ed.) J. Cramer, Vaduz.: 283-331, 1981

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