Art

J-GLOBAL ID：200902198118437914   Reference number：00A0089160

Funalenone, a Novel Collagenase Inbibitor Produced by Aspergillus niger.

フナレノン,Aspergillus nigerが生産する新規のコラゲナーゼ阻害剤

Author (6)： INOKOSHI J (Kitasato Univ., Tokyo, JPN) ,  SHIOMI K (Kitasato Inst., Tokyo, JPN) ,  MASUMA R (Kitasato Inst., Tokyo, JPN) ,  TANAKA H (Kitasato Univ., Tokyo, JPN) ,  YAMADA H (Kitasato Inst., Tokyo, JPN) ,  OMURA S (Kitasato Inst., Tokyo, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 52  Issue： 12  Page： 1095-1100  Publication year： Dec. 25, 1999 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *enzyme inhibitor ,...
Semi thesaurus term： *Aspergillus niger ,...

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JST classification (1)： Pharmacology of antibiotics in general  (GX05010R)

Substance index (2)： Funalenone ,  Xanthoherquein

Reference (10)：

• 1) WOESSNER, J. E; Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5: 2145-2154, 1991
• 2) FIRESTEIN, G. S.; M. M. PAINE & B. H. LITTMANN: Gene expression (collagenase, tissue inhibitor of metalloproteinase, complement and HLA-DR) in rheumatoid and osteoarthritic synovium. Arthritis Rheum. 34: 1094-1105,1991
• 3) WALAKOVITS, L. A.; N. BHARDWAJ, G. S. GALLICK & M. W. LARK: Detection of high levels of stromelysin and collagenase in synovial fluid in patients with rheumatoid arthritis and posttraumatic knee injury. Arthritis Rheum. 35: 35-42, 1992
• 4) LIOTTA, L. A.; K. TRYGGVASON, S. GARBISA, I. HART, C. M. FOLTZ & S. SHAFIE: Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature 284: 67-68, 1980
• 5) OKADA, Y; H. NAGASE & E. D. HARRIS, Jr.: A metalloproteinase from human rheumatoid synovirial fibroblasts that digests connective tissue matrix components. J. Biol. Chem. 261: 14245-14255, 1986

Terms in the title (4)： フナレノン ,  Aspergillus ,  コラゲナーゼ ,  阻害剤