Art

J-GLOBAL ID：200902201385909419   Reference number：07A0406427

Enzyme enhancement activity of N-octyl-β-valienamine on β-glucosidase mutants associated with Gaucher disease

Gaucher病に関連するβ-グルコシダーゼ変異体へのN-オクチル-β-バリエナミンの酵素増強活性

Author (12)： LEI Ke (Dep. of Child Neurology, Tottori Univ. Fac. of Medicine, Yonago 683-8503, JPN) ,  LEI Ke (Dep. of Pediatrics, Medical Coll. of Qingdao Univ., Qingdao, Shandong 266021, CHN) ,  NINOMIYA Haruaki (Dep. of Neurobiology, Tottori Univ. Fac. of Medicine, Yonago 683-8503, JPN) ,  SUZUKI Michitaka (Dep. of Neurobiology, Tottori Univ. Fac. of Medicine, Yonago 683-8503, JPN) ,  INOUE Takehiko (Dep. of Child Neurology, Tottori Univ. Fac. of Medicine, Yonago 683-8503, JPN) ,  SAWA Miwa (Central Res. Laboratories, Seikagaku Corp., Tokyo 207-0021, JPN) ,  IIDA Masami (Central Res. Laboratories, Seikagaku Corp., Tokyo 207-0021, JPN) ,  IDA Hiroyuki (Departments of Pediatrics and Gene Therapy, Inst. of DNA Medicine, Jikei Univ., Tokyo 105-8461, JPN) ,  ETO Yoshikatsu (Departments of Pediatrics and Gene Therapy, Inst. of DNA Medicine, Jikei Univ., Tokyo 105-8461, JPN) ,  OGAWA Seiichiro (Dep. of Applied Chemistry, Fac. of Sci. and Technol., Keio Univ., Yokohama 223-8522, JPN) ,  OHNO Kousaku (Dep. of Child Neurology, Tottori Univ. Fac. of Medicine, Yonago 683-8503, JPN) ,  SUZUKI Yoshiyuki (Clinical Res. Center, International Univ. of Health and Welfare, Otawara 324-8501, JPN)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1772  Issue： 5  Page： 587-596  Publication year： May. 2007 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Gaucher Disease ,...
Semi thesaurus term： enzyme regulation

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JST classification (2)： Enzyme in general  (EB09010D) ,  Congenital diseases,deformities in general.  (GD03010V)

Substance index (5)： NOEV ,  6α-(Dodecylamino)-4-(hydroxymethyl)-4-cyclohexene-1α,2β,3α-triol ,  6α-(Tetradecylamino)-4-(hydroxymethyl)-4-cyclohexene-1α,2β,3α-triol ,  6α-(Octadecylamino)-4-(hydroxymethyl)-4-cyclohexene-1α,2β,3α-triol ,  N,N-Dioctyl-β-valienamine

Terms in the title (7)： Gaucher病 ,  β-グルコシダーゼ ,  変異体 ,  バリエナミン ,  酵素 ,  増強 ,  活性