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J-GLOBAL ID：200902201832001195   Reference number：03A0380573

Changes in Blood Viscosity With Synthetic Protease Inhibitors

合成プロテアーゼ阻害剤による血液粘性の変化

Author (7)： HITOSUGI M (Dokkyo Univ. School of Medicine, Tochigi, JPN) ,  NIWA M (Chiba Univ. Commerce, Chiba, JPN) ,  TAKAHASHI T (Jikei Univ. School of Medicine, Tokyo, JPN) ,  KUROSU A (Dokkyo Univ. School of Medicine, Tochigi, JPN) ,  NIHEI H (Dokkyo Univ. School of Medicine, Tochigi, JPN) ,  NAGAI T (Dokkyo Univ. School of Medicine, Tochigi, JPN) ,  TOKUDOME S (Dokkyo Univ. School of Medicine, Tochigi, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 91  Issue： 4  Page： 334-336  Publication year： Apr. 01, 2003 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *blood viscosity ,...

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JST classification (1)： Basic research of drugs acting on blood and body fluid  (GW14010M)

Substance index (2)： Gabexate mesylate ,  Nafamostat mesilate

Reference (15)：

• 1 Iwaki M, Ino Y, Motoyoshi A, Ozeki M, Sato T, Kurumi M and Aoyama T: Pharmacological studies of FUT-175, nafamostat mesilate V, effects on the pancreatic enzymes and experimental acute pancreatitis in rats. Jpn J Pharmacol 41, 155 – 162 (1986)
• 2 Hitomi Y, Ikari N and Fujii S: Inhibitory effect of a new synthetic protease inhibitor (FUT-175) on the coagulation system. Haemostasis 15, 164 – 168 (1985)
• 3 Ohno H, Kosaki G, Kambayashi J, Imaoka S and Hirata F: FOY (ethyl p-(6-guanidinohexanoyloxy) benzoate) methanesulfonate as a serine protease inhibitor I, inhibition of thrombin and factor Xa in vitro. Thromb Res 19, 579 – 588 (1980)
• 4 Tamura Y, Hirado M, Okamura K, Minato Y and Fujii S: Synthetic inhibitors of trypsin, plasmin, kallikrein, thrombin, C1r, and C1 elastase. Biochim Biophys Acta 484, 417 – 422 (1977)
• 5 Aoyama T, Ino Y, Ozeki M, Oda M, Sato T, Koshiyama Y, Suzuki S and Fujita M: Pharmacological studies of FUT-175, nafamostat mesilate I, inhibition of protease activity in in vitro and in vivo experiments. Jpn J Pharmacol 35, 203 – 227 (1984)

Terms in the title (2)： プロテアーゼ阻害剤 ,  血液粘性