Art

J-GLOBAL ID：200902202631407092   Reference number：08A0188345

Inhibitory Effect of Agaricu blazei Murill Components on Abnormal Collagen Fiber Formation in Human Hepatocarcinoma Cells

ヒト肝癌細胞株における異常コラーゲン繊維形成に対するAgaricu blazei(ハラタケ属)成分の阻害作用

Author (3)： SORIMACHI Kenji (Educational Support Center, Dokkyo Medical Univ.) ,  AKIMOTO Kazumi (Clinical Medicine Res. Center, Dokkyo Medical Univ.) ,  KOGE Takashi (BHN Co., Ltd.)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 72  Issue： 2  Page： 621-623 (J-STAGE)  Publication year： 2008 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Agaricus ,...
Semi thesaurus term： Agaricus blazei Murrill ,...

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JST classification (2)： Food chemistry,nutritional value  (FJ01020J) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Ethanol

Reference (18)：

• 1) Kawagishi, H., Inagaki, R., Kano, T., Mizuno, T., Shimura, K., Ito, H., Hagiwara, T., and Nakamura, T., Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting bodies. Carbohydr. Res., 186, 267–273 (1989).
• 2) Itoh, H., Ito, H., Amano, H., and Noda, H., Inhibitory action of a (1→6)-β-D-glucan-protein complex (F-III-2-b) isolated from Agaricus blazei Murill (“Himematsutake”) on Meth A fibrosarcoma-bearing mice and its antitumor mechanism. Jpn. J. Pharmacol., 66, 265–271 (1994).
• 3) Ito, H., Shimura, K., Itoh, H., and Kawade, M., Antitumor effects of a new polysaccharide-protein complex (ATOM) prepared from Agaricus blazei (Iwade strain 101) “Himematsutake” and its mechanisms in tumor bearing mice. Anticancer Res., 17, 277–284 (1997).
• 4) Ebina, T., and Fujimiya, Y., Antitumor effect of a peptide-glucan preparation extracted from Agaricus blazei in a double-grafted tumor system in mice. Biotherapy, 11, 259–265 (2001).
• 5) Ohno, N., Furukawa, M., Miura, N.-N., Adachi, Y., Motoi, M., and Yadomae, T., Antitumor β-glucan from the cultured body of Agaricus blazei. Biol. Pharm. Bull., 24, 820–828 (2001).

Terms in the title (6)： ヒト ,  肝癌 ,  細胞株 ,  コラーゲン繊維 ,  ハラタケ属 ,  阻害作用