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J-GLOBAL ID：200902205753910070   Reference number：08A0739595

新規うつ病治療標的分子としてのfrizzled-3 proteinの可能性

Author (6)： YAMADA MITSUHIKO (国立精神・神経セ 精神保健研) ,  YAMADA MISA (国立精神・神経セ 精神保健研) ,  TAKAHASHI KO (国立精神・神経セ 精神保健研) ,  MARUYAMA YOSHIAKI (国立精神・神経セ 精神保健研) ,  OZAKI NORIO (名古屋大 大学院医学系研究科 細胞情報医学専攻 脳神経病態制御学) ,  IWATA NAKAO (藤田保健衛生大 医 精神医学)
Material： 臨床薬理の進歩  (Recent Advances in Clinical Pharmacology)
Issue： 29  Page： 221-225  Publication year： Jul. 08, 2008 
JST Material Number： Y0720A  ISSN： 0914-4366  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *depression(disease) ,...
Semi thesaurus term： *Frizzled protein

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JST classification (2)： Basic psychiatry  (GR01020I) ,  Basic research of psychotropic drugs  (GW03100Y)

Reference (19)：

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• Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA & Nathans J. A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem 1996; 271: 4468-4476.
• Kirikoshi H, Sagara N, Saitoh T, Tanaka K, Sekihara H, Shiokawa K & Katoh M. Molecular cloning and characterization of human FGF-20 on chromosome 8p21. 3-p22. Biochem Biophys Res Commun 2000; 274: 337-343.
• Chan SD, Karpf DB, Fowlkes ME, Hooks M, Bradley MS, Vuong V, Bambino T, Liu MY, Arnaud CD & Strewler GJ. Two homologs of the Drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues. J Biol Chem 1992; 267: 25202-25207.

Terms in the title (4)： うつ病 ,  治療標的分子 ,  Frizzled ,  可能性