Art

J-GLOBAL ID：200902208884447994   Reference number：04A0096922

Helquinoline, a New Tetrahydroquinoline Antibiotic from Janibacter limosus Hel 1.

Janibacter limosus Hel1株由来の新規テトラヒドロキノリン系抗生物質ヘルキノリン

Author (6)： ASOLKAR R N (Univ. Goettingen, Goettingen, DEU) ,  SCHROEDER D (Univ. Goettingen, Goettingen, DEU) ,  HECKMANN R (Univ. Braunschweig, Braunschweig, DEU) ,  LANG S (Univ. Braunschweig, Braunschweig, DEU) ,  WAGNER-DOEBLER I (National Res. Inst. Biotechnol., Braunschweig, DEU) ,  LAATSCH H (Univ. Goettingen, Goettingen, DEU)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 57  Issue： 1  Page： 17-23  Publication year： Jan. 25, 2004 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,...
Semi thesaurus term： tetrahydroquinoline ,...

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JST classification (1)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C)

Substance index (3)： Kynuramine ,  Helquinoline ,  N-Acetylkynuramine

Reference (28)：

• 1) a) JOHNSON, J. V.; S. RAUCKMAN, P. D. BACCANARI & B. ROTH: 2,4-Diamino-5-benzylpyrimidines & analogues as antibacterial agents 12. 1,2-Dihydroquinolylmethyl analogues with high activity and specificity for bacterial dihydrofolate reductase. J. Med. Chem. 32: 1942-1949, 1989
• b) CARLING, R. W.; P. D. LEESON, A. M. MOSELEY, R. BAKER, A. C. FOSTER, S. GRIMWOOD, J. A. KEMP & G. R. MARSHALL: 2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor. J. Med. Chem. 35: 1942-53, 1992
• 2) KOKWARO, G. O. & G. TAYLOR: Partitioning of oxaminiquine into brain tissue following intravenous administration to female Wistar rats. Drug Chem. Toxicol. 13: 347-354, 1990
• 3) KIMURA, T.; S. IMANISHI & M. ARITA: Electrophysiologic effects of nicainoprol, a putative class I antiarrhythmic agent, on guinea pig ventricular papillary muscle. J. Cardiovasc. Pharmacol. 13: 767-773, 1989
• 4) OMURA, S. & A. NAKAGAWA: Structure of virantmycin, a novel antiviral antibiotic. Tetrahedron Lett. 22: 2199-2202, 1981

Terms in the title (3)： 株 ,  抗生物質 ,  キノリン