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J-GLOBAL ID：200902210814072513   Reference number：06A0236100

Epithelial Cells Secrete Interleukin-8 in Response to Adhesion and Invasion of Diffusely Adhering Escherichia coli Lacking Afa/Dr Genes

Afa/Dr遺伝子を欠く拡散接着性Escherichia coliの接着及び侵入に応答して上皮細胞はインターロイキン8を分泌する

Author (5)： MERAZ Ismail Mustafa (Dep. of Food and Human Health Sciences, Graduate School of Human Life Sci., Osaka City Univ.) ,  ARIKAWA Kentaro (Dep. of Food and Human Health Sciences, Graduate School of Human Life Sci., Osaka City Univ.) ,  OGASAWARA Jun (Dep. of Microbiology and Health, Osaka City Inst. of Public Health and Environmental Sciences) ,  HASE Atsushi (Dep. of Microbiology and Health, Osaka City Inst. of Public Health and Environmental Sciences) ,  NISHIKAWA Yoshikazu (Dep. of Food and Human Health Sciences, Graduate School of Human Life Sci., Osaka City Univ.)
Material： Microbiology and Immunology  (Microbiol Immunol)
Volume： 50  Issue： 3  Page： 159-169 (J-STAGE)  Publication year： 2006 
JST Material Number： F0715A  ISSN： 0385-5600  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *bacterial infection (phenomenon) ,...
Semi thesaurus term： *enteropathogenic Escherichia coli ,...

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JST classification (2)： Physiology and pathogenicity of microbial infection  (EG03053T) ,  Immunological reaction in general  (ED03010T)

Substance index (1)： Wortmannin

Reference (54)：

• ARIKAWA, K. Interleukin-8 secretion by epithelial cells infected with diffusely adherent Escherichia coli possessing Afa adhesin-coding genes. Microbiol. Immunol. 2005, 49, 493-503
• BAQUI, A. H. Enteropathogens associated with acute and persistent diarrhea in Bangladeshi children less than 5 years of age. J. Infect. Dis. 1992, 166, 792-796
• BETIS, F. The Afa/Dr adhesins of diffusely adhering Escherichia coli stimulate interleukin-8 secretion, activate mitogen-activated protein kinases, and promote polymorphonuclear transepithelial migration in T84 polarized epithelial cells. Infect. Immun. 2003, 71, 1068-1074
• BETIS, F. Afa/Dr diffusely adhering Escherichia coli infection in T84 cell monolayers induces increased neutrophil transepithelial migration, which in turn promotes cytokine-dependent upregulation of decay-accelerating factor (CD55), the receptor for Afa/Dr adhesins. Infect. Immun. 2003, 71, 1774-1783
• BISWAS, D. Role of microfilaments and microtubules in the invasion of INT-407 cells by Campylobacter jejuni. Microbiol. Immunol. 2003, 47, 469-473

Terms in the title (8)： 拡散 ,  接着性 ,  Escherichia ,  侵入 ,  応答 ,  上皮細胞 ,  インターロイキン8 ,  分泌