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J-GLOBAL ID：200902210925263300   Reference number：09A0556742

NEW CYTOTOXIC NOR- AND BISNORDITERPENE DILACTONES, MAKILACTONES A-D, FROM PODOCARPUS MACROPHYLLUS D. DON

Podocarpus macrophyllus D. Don由来の新規細胞毒性ノル-及びビスノルジテルペンジラクトン,マキラクトンA~D

Author (9)： SATO Kimihiko (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  SUGAWARA Keito (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  TAKEUCHI Hirono (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  PARK Hyun-Sun (Kochi Prefectural Makino Botanical Garden, Kochi, JPN) ,  AKIYAMA Toshiyuki (Kochi Prefectural Makino Botanical Garden, Kochi, JPN) ,  KOYAMA Tetsuo (Kochi Prefectural Makino Botanical Garden, Kochi, JPN) ,  FUKAYA Haruhiko (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  AOYAGI Yutaka (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  TAKEYA Koichi (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 78  Issue： 6  Page： 1453-1462  Publication year： Jun. 01, 2009 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *diterpene ,  lactone ,  Podocarpaceae ,  solvent extraction ,  isolation (separation) ,  *molecular structure ,  crystal structure analysis ,  cytotoxicity ,  aliphatic alcohol ,  Acrogymnospermae
Semi thesaurus term： Podocarpus macrophyllus D. Don

JST classification (2)： Diterpenes,sesterterpenes  (CF10023R) ,  Gevmetry of molecules in general  (BH05021S)

Substance index (8)： Methanol ,  Makilactone A ,  Makilactone B ,  Makilactone C ,  Makilactone D ,  Nagilactone F ,  2β-Hydroxynagilactone F ,  (3S)-3α-Hydroxy-3aβ,10bα-dimethyl-7β-isopropyl-1,2,3,3a,5aβ,7,10b,10cβ-octahydro-4H,9H-furo[2′,3′,4′:4,5]naphtho[2,1-c]pyran-4,9-dione

Reference (12)：

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• K. Sato, K. Sugawara, H. Takeuchi, H. Park, T. Akiyama, T. Koyama, Y. Aoyagi, K. Takeya, and T. Tsugane, Chem. Pharm. Bull., 2008, 56, 1691.

Terms in the title (4)： Podocarpus ,  DON ,  細胞毒性 ,  ラクトン