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J-GLOBAL ID：200902212942673263   Reference number：05A0895218

Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation

ヒトタウ変異体(N279K)を発現するトランスジェニックマウスは神経原線維変化形成無しの認識障害依存変異を示す

Author (8)： TANIGUCHI Taizo (Lab. of Molecular Pharmacology, Biosignal Res. Center, Kobe Univ., 1-1 Rokkodai-cyo, Nada-ku, Kobe 657-8501, JPN) ,  TANIGUCHI Taizo (Behavioral and Medical Sci. Res. Consortium, 2-5-7 Tamachi, Akashi, Hyogo 673-0025, JPN) ,  DOE Nobutaka (Dep. of Integrated Psychological Sci., Kwansei Gakuin Univ., Uegahara, Nishinomiya 662-8501, JPN) ,  MATSUYAMA Shogo (Dep. of Genome Sciences, Kobe Univ. Graduate School of Medicine, 7-5-1 Kusunoki-cho, Cyuo-ku, Kobe 650-0017, JPN) ,  KITAMURA Yoshihisa (Behavioral and Medical Sci. Res. Consortium, 2-5-7 Tamachi, Akashi, Hyogo 673-0025, JPN) ,  MORI Hiroshi (Dep. of Neuroscience, Osaka City Univ. Medical School, 1-4-3 Asahi-cho, Abeno-ku, Osaka 545-8585, JPN) ,  SAITO Naoaki (Lab. of Molecular Pharmacology, Biosignal Res. Center, Kobe Univ., 1-1 Rokkodai-cyo, Nada-ku, Kobe 657-8501, JPN) ,  TANAKA Chikako (Lab. of Molecular Pharmacology, Biosignal Res. Center, Kobe Univ., 1-1 Rokkodai-cyo, Nada-ku, Kobe 657-8501, JPN)
Material： FEBS Letters  (for the Rapid Publication of Short Reports in Biochemistry, Biophysics)
Volume： 579  Issue： 25  Page： 5704-5712  Publication year： Oct. 24, 2005 
JST Material Number： D0575A  ISSN： 0014-5793  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： dementia

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JST classification (1)： Basic neurology  (GN01020W)

Terms in the title (6)： 変異体 ,  発現 ,  トランスジェニックマウス ,  神経原線維変化 ,  認識障害 ,  変異