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J-GLOBAL ID：200902213933111860   Reference number：07A0690421

Association analysis of glutathione-S-transferase P1 (GSTP1) polymorphism with urothelial cancer susceptibility and myelosuppression after M-VAC chemotherapy

M-VAC化学療法後のグルタチオン-S-トランスフェラーゼP1(GSTP1)多型性と尿路上皮癌感受性および骨髄抑制の関連分析

Author (6)： YOKOMIZO Akira (Kyushu Univ. Graduate School of Medical Sci.) ,  YAMAMOTO Ken (Kyushu Univ., Fukuoka, JPN) ,  KINUKAWA Naoko (Kyushu Univ. Graduate School of Medical Sci.) ,  TSUNODA Toshiyuki (Kyushu Univ. Graduate School of Medical Sci.) ,  KOGA Hirofumi (Kyushu Univ. Graduate School of Medical Sci.) ,  NAITO Seiji (Kyushu Univ. Graduate School of Medical Sci.)
Material： International Journal of Urology  (Int J Urol)
Volume： 14  Issue： 6  Page： 500-504  Publication year： Jun. 2007 
JST Material Number： W1347A  ISSN： 0919-8172  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： dichlorodiammine platinum ,...

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JST classification (2)： Drug therapy(=pharmacotherapy)for urogenital diseases  (GM05020V) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (3)： Methotrexate ,  Vinblastine ,  Doxorubicin

Reference (25)：

• YOKOMIZO, A. Markedly decreased expression of glutathione S-transferase pi gene in human cancer cell lines resistant to buthionine sulfoximine, an inhibitor of cellular glutathione synthesis. J. Biol. Chem. 1995, 270, 19451-19457
• STRANGE, RC. Glutathione-S-transferase family of enzymes. Mutat. Res. 2001, 482, 21-26
• DEBES, JD. Glutathione-S-transferase P1 polymorphism I105V in familial and sporadic prostate cancer. Cancer Genet. Cytogenet. 2004, 155, 82-86
• NAITO, S. Molecular analysis of mechanisms regulating drug sensitivity and the development of new chemotherapy strategies for genitourinary carcinomas. World J. Surg. 2000, 24, 1183-1186
• NAITO, S. Mechanisms of drug resistance in chemotherapy for urogenital carcinoma. Int. J. Urol. 1999, 6, 427-439

Terms in the title (9)： VAC ,  化学療法 ,  グルタチオン-S-トランスフェラーゼ ,  GSTP1 ,  多型性 ,  尿路上皮癌 ,  感受性 ,  骨髄抑制 ,  分析