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J-GLOBAL ID：200902215132810220   Reference number：04A0429216

Calcineurin Contributes to the Enhancing Effect of Adenosine on Nerve Growth Factor-Induced Neurite Outgrowth via the Decreased Duration of p38 Mitogen-Activated Protein Kinase Phosphorylation

カルシニューリンはp38マイトジェン活性化蛋白質キナーゼのリン酸化の減少した持続を介した神経成長因子誘導による神経突起の伸長に及ぼすアデノシンの増強効果に寄与する

Author (5)： MUROI Y (Obihiro Univ. Agriculture and Veterinary Medicine, Hokkaido, JPN) ,  ISHII T (Obihiro Univ. Agriculture and Veterinary Medicine, Hokkaido, JPN) ,  TERAMOTO K (Obihiro Univ. Agriculture and Veterinary Medicine, Hokkaido, JPN) ,  HORI M (Univ. Tokyo, Tokyo, JPN) ,  NISHIMURA M (Obihiro Univ. Agriculture and Veterinary Medicine, Hokkaido, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 95  Issue： 1  Page： 124-131  Publication year： May. 20, 2004 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *calcineurin ,...
Semi thesaurus term： phosphoprotein phosphatase ,...

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JST classification (3)： Biological function  (EB03040U) ,  Biological function  (EB04020F) ,  Cell physiology in general  (EF02010S)

Substance index (2)： Adenosine ,  Tacrolimus

Reference (21)：

• 1 Greene LA, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA. 1976;73:2424–2428.
• 2 Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell. 1995;80:179–185.
• 3 Cowley S, Paterson H, Kemp P, Marshall CJ. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell. 1994;77:841–852.
• 4 Morooka T, Nishida E. Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells. J Biol Chem. 1998;273:24285–24288.
• 5 Huffaker T, Corcoran T, Wagner JA. Adenosine inhibits cell division and promotes neurite extension in PC12 cells. J Cell Physiol. 1984;120:188–196.

Terms in the title (9)： カルシニューリン ,  P38 ,  マイトジェン活性化蛋白質キナーゼ ,  リン酸化 ,  神経成長因子 ,  誘導 ,  神経突起 ,  アデノシン ,  増強