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J-GLOBAL ID：200902215377773398   Reference number：04A0575571

Involvement of Reactive Oxygen Species (ROS) in the Induction of Genetic Instability by Radiation

照射による遺伝的不安定性の誘発における反応性酸素種(ROS)の関与

Author (5)： TOMINAGA H (Nagasaki Univ., Nagasaki, JPN) ,  KODAMA S (Nagasaki Univ., Nagasaki, JPN) ,  MATSUDA N (Nagasaki Univ., Nagasaki, JPN) ,  SUZUKI K (Nagasaki Univ., Nagasaki, JPN) ,  WATANABE M (Nagasaki Univ., Nagasaki, JPN)
Material： Journal of Radiation Research  (J Radiat Res)
Volume： 45  Issue： 2  Page： 181-188  Publication year： Jun. 15, 2004 
JST Material Number： F0337A  ISSN： 0449-3060  CODEN： JRARAX  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *active oxygen ,...

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JST classification (1)： Influence on cellular levels  (EK02030D)

Substance index (1)： L-Ascorbic acid 2-phosphate

Reference (26)：

• 1. Riley, P. A. (1994) Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int. J. Radiat. Biol. 65: 27- 33.
• 2. Wallace, S. S. (1998) Enzymatic processing of radiation-induced free radical damage in DNA. Radiat. Res. 150: S60-S79.
• 3. Dent, P., Yacoub, A., Contessa, J., Caron, R., Amorino, G., Valerie, K. Hagen, M. P., Grant, S. and Schmidt-Ullrich, R. (2003) Stress and radiation-induced activation of multiple intracellular signaling pathways. Radiat. Res. 159: 283-300.
• 4. Roy, K., Kodama, S., Suzuki, K., Fukase, K. and Watanabe, M. (2000) Hypoxia relieves X-ray-induced delayed effects in normal human embryo cells. Radiat. Res. 154: 659-666.
• 5. Kashino, G., Kodama, S., Nakayama, Y., Suzuki, K., Fukase, K., Goto, M. and Watanabe, M. (2003) Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells. Free Radical Biol. Med. 15: 438- 443.

Terms in the title (4)： 遺伝的不安定性 ,  誘発 ,  反応性酸素種 ,  ROS