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J-GLOBAL ID：200902216019099010   Reference number：06A0676929

Modification by curcumin of mutagenic activation of carcinogenic N-nitrosamines by extrahepatic cytochromes P-450 2B1 and 2E1 in rats

ラットでの肝臓外チトクロームP-450 2B1および2E1による発癌性N-ニトロソアミン類の変異原性活性化のクルクミンによる調節

Author (6)： MORI Yukio (Gifu Pharmaceutical Univ., Gifu, JPN) ,  TATEMATSU Kenjiro (Gifu Pharmaceutical Univ., Gifu, JPN) ,  KOIDE Akihiro (Gifu Pharmaceutical Univ., Gifu, JPN) ,  SUGIE Shigeyuki (Kanazawa Medical Univ., Ishikawa, JPN) ,  TANAKA Takuji (Kanazawa Medical Univ., Ishikawa, JPN) ,  MORI Hideki (Gifu Univ., Gifu, JPN)
Material： Cancer Science  (Cancer Sci)
Volume： 97  Issue： 9  Page： 896-904  Publication year： Sep. 2006 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： Rattus ,...
Semi thesaurus term： CYP2B1 ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (2)： N-Nitrosomethylbenzylamine ,  Curcumin

Reference (76)：

• LIN, HJ. Zinc levels in serum, hair, and tumors from patients with esophageal carcinoma. Nutr Rep Int. 1977, 15, 635-643
• YANG, CS. Research on esophageal cancer in China : a review. Cancer Res. 1980, 40, 2633-2644
• National Academy of Sciences. The Health Effects of Nitrate, Nitrite, and N-Nitroso Compounds. 1981
• VAN RENSBURG, SJ. Epidemiologic and dietary evidence for a specific nutritional predisposition to esophageal cancer. J Natl Cancer Inst. 1981, 67, 243-251
• DRUCKREY, H. Organotropic carcinogenic effects of 65 various N-nitrosocompounds on BD rats. Z Krebsforsch. 1967, 69, 103-201

Terms in the title (9)： ラット ,  肝臓 ,  チトクロームP-450 ,  発癌性 ,  ニトロソアミン類 ,  変異原性 ,  活性化 ,  クルクミン ,  調節