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J-GLOBAL ID：200902216947022592   Reference number：05A0905583

Inhibitory Effect of Thiopental on Ultra-rapid Delayed Rectifier K⁺ Current in H9c2 Cells

H9c2細胞における超急速遅延整流K⁺電流へのチオペンタールの阻害性作用

Author (8)： SUZUKI Hideki (Dep. of Pediatrics, Fukushima Medical Univ., School of Medicine) ,  MOMOI Nobuo (Dep. of Pediatrics, Fukushima Medical Univ., School of Medicine) ,  ONO Tomoyuki (Dep. of Pharmacology, Fukushima Medical Univ., School of Medicine) ,  MAEDA Sachiko (Dep. of Pharmacology, Fukushima Medical Univ., School of Medicine) ,  SHIKAMA Yayoi (Dep. of Pharmacology, Fukushima Medical Univ., School of Medicine) ,  MATSUOKA Isao (Dep. of Pharmacology, Fukushima Medical Univ., School of Medicine) ,  SUZUKI Hitoshi (Dep. of Pediatrics, Fukushima Medical Univ., School of Medicine) ,  KIMURA Junko (Dep. of Pharmacology, Fukushima Medical Univ., School of Medicine)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 99  Issue： 2  Page： 177-184 (J-STAGE)  Publication year： 2005 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： current generation ,...
Semi thesaurus term： voltage clamp method ,...

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JST classification (2)： Drugs acting on circulatory system in general  (GW07010C) ,  Cell physiology in general  (EF02010S)

Substance index (6)： Thiopental ,  Chromanol 293B ,  Nifedipine ,  E-4031 ,  Tetraethylammonium ,  4-Aminopyridine

Reference (32)：

• 1 Nerbonne JM. Molecular basis functional voltage-gated K⁺ channel diversity in the mammalian myocardium. J Physiol (Lond). 2000;525:285–298.
• 2 Roden DM, Lazzara R, Rosen M, Schhartz PJ, Towbin J, Vincent GM. Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS. Circulation. 1996;94:1996–2012.
• 3 Morey TE, Martynyuk AE, Napolitano CA, Raatikainen MJ, Guyton TS, Dennis DM. Ionic basis of the differential effects of intravenous anesthetics on erythromycin-induced prolongation of ventricular repolarization in the guinea pig heart. Anesthesiology. 1997;87:1172–1181.
• 4 Martynyuk AE, Morey TE, Raatikainen MJ, Seubert CN, Dennis DM. Ionic mechanisms mediating the differential effects of methohexital and thiopental on action potential duration in guinea pig and rabbit isolated ventricular myocytes. Anesthesiology. 1999;90:156–164.
• 5 Frankl WS, Poole-Wilson PA. Effects of thiopental on tension development, action potential, and exchange of calcium and potassium in rabbit ventricular myocardium. J Cardiovasc Pharmacol. 1981;3:554–565.

Terms in the title (4)： H9c2細胞 ,  急速 ,  チオペンタール ,  阻害