Art

J-GLOBAL ID：200902217823353406   Reference number：09A1236785

Dynasore, a dynamin inhibitor, suppresses lamellipodia formation and cancer cell invasion by destabilizing actin filaments

ダイナミン阻害剤ダイナソアはアクチン繊維を不安定化することにより葉状仮足形成と癌細胞浸潤を抑制する

Author (10)： YAMADA Hiroshi (Dep. of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  ABE Tadashi (Dep. of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  LI Shun-ai (Dep. of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  MASUOKA Yuki (Dep. of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  ISODA Mihoko (Dep. of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  WATANABE Masami (Dep. of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  NASU Yasutomo (Dep. of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  KUMON Hiromi (Dep. of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...) ,  ASAI Akira (Center for Drug Discovery, Graduate School Pharmaceutical Sciences, Univ. of Shizuoka, 52-1, Yada, Suruga-ku ...) ,  TAKEI Kohji (Dep. of Neuroscience, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ., 2-5-1 ...)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 390  Issue： 4  Page： 1142-1148  Publication year： Dec. 25, 2009 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： GTPase ,  microtubule-associated protein ,  Membrane Proteins ,  enzyme inhibitor ,  actin filament ,  *Cell Membrane ,  morphogenesis ,  *tumor invasion ,  actin ,  tumor cell ,  cultured cell ,  *antitumor action ,  subcellular distribution ,  F actin ,  U2OS cell ,  Dynamins ,  *lamellipodium ,  *Endomembrane system
Semi thesaurus term： *ダイナソア

JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Terms in the title (6)： ダイナミン ,  阻害剤 ,  アクチン繊維 ,  葉状仮足 ,  癌細胞 ,  浸潤