Art

J-GLOBAL ID：200902219971345695   Reference number：07A0586985

Controlled Release of Simvastatin Acid Using Cyclodextrin Inclusion System

シクロデキストリン包接系を用いたシンバスタチン酸の放出制御

Author (8)： YOSHINARI Masao (Tokyo Dental Coll., Chiba, JPN) ,  MATSUZAKA Kenichi (Tokyo Dental Coll., Chiba, JPN) ,  HASHIMOTO Sadamitsu (Tokyo Dental Coll., Chiba, JPN) ,  ISHIHARA Kazuyuki (Tokyo Dental Coll., Chiba, JPN) ,  INOUE Takashi (Tokyo Dental Coll., Chiba, JPN) ,  ODA Yutaka (Tokyo Dental Coll., Chiba, JPN) ,  IDE Takaharu (Kyushu Univ., Fukuoka, JPN) ,  TANAKA Teruo (Kyushu Univ., Fukuoka, JPN)
Material： Dental Materials Journal  (Dent Mater J)
Volume： 26  Issue： 3  Page： 451-456  Publication year： May. 2007 
JST Material Number： Y0283A  ISSN： 0287-4547  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cyclodextrin ,...
Semi thesaurus term： BMP2

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JST classification (3)： Physical pharmacy  (GY01012A) ,  Physicochemical characteristics of drugs  (GV01060M) ,  Basic dentistry(= odontology)  (GT01020O)

Substance index (1)： Simvastatin acid

Reference (21)：

• 1) Mundy G, Garrett R, Harris S, Chan J, Chen D, Rossini G, Boyce B, Zhao M, Gutierrez G. Stimulation of bone formation in vitro and in rodents by statins. Science 1999; 286:1946-1949.
• 2) Garrett IR, Gutierrez G, Mundy GR. Statins and bone formation. Curr Pharm Des 2001; 7:715-736.
• 3) Ayukawa Y, Okamura A., Koyano K. Simvastatin stimulates bone formation around titanium implants in rat tibiae. Clin Oral Impl Res 2004; 15:346-350.
• 4) von Stechow D, Fish S, Yahalom D, Bab I, Chorev M, Müller R, Alexander JM. Does simvastatin stimulate bone formation in vivo? BMC Musculoskelet Disord 2003; 4:1-10.
• 5) Prueksaritanont T, Qiu Y, Mu L, Michel K, Brunner J, Richards KM, Lin JH. Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: effects of gemfibrozil. Pharm Res 2005; 22:1101-1109.

Terms in the title (3)： シクロデキストリン ,  シンバスタチン酸 ,  放出