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J-GLOBAL ID：200902221406582831   Reference number：07A0177166

Isolation of Tryptophol as an Apoptosis-Inducing Component of Vinegar Produced from Boiled Extract of Black Soybean in Human Monoblastic Leukemia U937 Cells

ヒト単芽球性白血病U937細胞における黒大豆の沸騰抽出物から造った食酢のアポトーシス誘導成分としてのトリプトホールの分離

Author (6)： INAGAKI Shyuichiro (Graduate School of Sci. and Technol., Kumamoto Univ.) ,  MORIMURA Shigeru (Graduate School of Sci. and Technol., Kumamoto Univ.) ,  GONDO Kazunobu (Graduate School of Sci. and Technol., Kumamoto Univ.) ,  TANG Yueqin (Graduate School of Sci. and Technol., Kumamoto Univ.) ,  AKUTAGAWA Hiroshi (Marumiya Co., Ltd.) ,  KIDA Kenji (Graduate School of Sci. and Technol., Kumamoto Univ.)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 71  Issue： 2  Page： 371-379 (J-STAGE)  Publication year： 2007 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Glycine max ,...
Semi thesaurus term： black soybean ,...

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JST classification (3)： Cell division and proliferation  (EF02020D) ,  Fermented seasonings  (FK04030S) ,  Food chemistry,nutritional value  (FJ01020J)

Substance index (1)： Tryptophol

Reference (38)：

• 1) Furuta, S., Takahashi, M., Takahata, Y., Nishiba, Y., Oki, T., Masuda, M., Kobayashi, M., and Suda, I., Radical-scavenging activities of soybean cultivars with black seed coats. Food Sci. Technol. Res., 9, 73–75 (2003).
• 2) Liao, H. F., Chou, C. J., Wu, S. H., Khoo, K. H., Chen, C. F., and Wang, S. Y., Isolation and characterization of an active compound fron black soybean (Glycine max (L.) Merr.) and its effect on proliferation and differentiation of human leukemic U937 cells. Anticancer Drugs, 12, 841–846 (2001).
• 3) Yamai, M., Tsumura, K., Kimura, M., Fukuda, S., Murakami, T., and Kimura, Y., Antiviral activity of a hot water extract of black soybean against human respiratory illness virus. Biosci. Biotechnol. Biochem., 67, 1071–1079 (2003).
• 4) Kikuchi, H., Matsuyama, Z., and Nozaki, Y., In vivo effect of boiled water extract from black soybean on the fluidity of whole blood through capillary-model microchannels. Hemorheology and Related Research (in Japanese), 2, 61–66 (1999).
• 5) Nanda, K., Miyoshi, N., Nakamura, Y., Shimoji, Y., Tamura, Y., Nishikawa, Y., Uenakai, K., Kohno, H., and Tanaka, T., Extract of vinegar “Kurosu” from unpolished rice inhibits the proliferation of human cancer cells. J. Exp. Clin. Cancer Res., 23, 69–75 (2004).

Terms in the title (9)： ヒト ,  芽球性白血病 ,  U937細胞 ,  黒大豆 ,  沸騰 ,  抽出物 ,  食酢 ,  アポトーシス誘導 ,  トリプトホール